Forum on Neuroscience and Nervous System Disorders 2017 Annual Report (2018) / Chapter Skim
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Forum on Neuroscience and Nervous System Disorders: 2017 Annual Report
Forum on Neuroscience and Nervous System Disorders: 2017 Annual Report
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Forum on Neuroscience and Nervous System Disorders 2017 Annual Report
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In addition to continued work on more traditional small molecule drug approaches, individuals and organizations are increasingly working on a host of newer The National Academies of therapeutic strategies, including biologics for the brain, gene therapies, genome Sciences, Engineering, and engineering, and implantable and noninvasive devices. Efforts are also under way Medicine's Forum on to harness emerging technologies and analytical methods, such as artificial Neuroscience and Nervous System intelligence and machine learning focused on "big data." Disorders provides an important The National Academies of Sciences, Engineering, and Medicine's Forum on venue for candid discussions Neuroscience and Nervous System Disorders provides an important venue for about emerging and critical candid discussions about emerging and critical issues among key stakeholders, including federal agencies that serve as research sponsors and regulators; the issues among key stakeholders.
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The Forum will also invite members of the legal community, including federal and state judges, to join its members and other scientists in exploring how emerging neurotechnologies will impact the legal system. In June, the Forum will bring interested individuals together to discuss the Story Landis tremendous promise -- and challenges -- associated with using mobile technology Vice-Chair devices to predict, diagnose, monitor, and develop treatments for brain disorders.
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Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Blood–Brain Barrier The blood–brain barrier (BBB) presents a special challenge to the development of therapeutics for many CNS disorders.
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The Forum hosted a public workshop including key experts from academia, government, the biotechnology and pharmaceutical sector, disease-focused organizations, and other interested stakeholders to explore the current development of novel methods for traversing the BBB to deliver therapeutics for nervous system disorders and to identify potential opportunities for moving the field forward. Success in these endeavors Advancing Therapeutic Development for Pain and Opioid Use would greatly increase the Disorders Through Public–Private Partnerships armamentarium of potential Pain is a leading cause of disability in the United States, affecting more people than drugs for treating psychiatric cancer, diabetes, and heart disease combined.
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To begin to explore the potential impact of emerging neurotechnologies on the legal system, the Forum, in collaboration with the National Academies' Committee on Science, Technology, and Law, will host a public workshop, bringing together leaders from academia, judicial and law enforcement systems, industry, government and regulatory agencies, nonprofit foundations and other stakeholders to advance efforts to identify and evaluate the potential positive and negative effects of emerging neurotechnologies on the legal system.
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Transgenic and Chimeric Neuroscience Research: Exploring the Scientific Opportunities Afforded by New Nonhuman Primate Models The translational disconnect from preclinical studies with predominantly rodent animal models to human clinical trials remains a key challenge associated with the lagging development of therapies for brain disorders. Since 2012, the Forum has hosted a series of workshops examining different aspects of this challenge, including maximizing the translation of effective therapies from animal models to clinical practice and exploring the evidence needed to bring compounds that appear to be safe into human efficacy trials.
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Clinical Research Data Sharing The Forum is participating in a clinical research data sharing activity that is a collaboration across four National Academies forums that focus on neuroscience; drug discovery, development, and translation; genomics; and cancer. Building on the 2015 report published by the Institute of Medicine, Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk, the group's goals are to improve coordination and collaboration among stakeholders engaged in activities related to data sharing The Forum established a working and to support implementation efforts by creating a mechanism for collaborative participants to identify priority issues and organize activities.
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Using tools set forth by the World Health Organization, the Forum, in collaboration with global entities, is continuing to explore additional opportunities to contribute in this area, with a focus on maternal and child mental and neurological health.
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Fox Foundation for Parkinson's Research Sarah Caddick Inez Jabalpurwala Brain Canada Foundation David Shurtleff Gatsby Charitable Foundation National Center for Complementary Rosa Canet-Aviles Frances Jensen and Integrative Health Foundation for the National Institutes University of Pennsylvania Paul Sieving of Health George Koob National Eye Institute Maria Carrillo National Institute on Alcohol Abuse Andrew Welchman Alzheimer's Association and Alcoholism Wellcome Trust E Antonio Chiocca Walter Koroshetz Doug Williamson Harvard Medical School National Institute of Neurological Lundbeck Timothy Coetzee Disorders and Stroke Nora Volkow National Multiple Sclerosis Society John Krystal National Institute on Drug Abuse Jonathan Cohen Yale University School of Medicine Stevin Zorn Princeton University Alan Leshner George & Anne Ryan Institute for Fay Lomax Cook American Association for the Advancement Neuroscience and MindImmune National Science Foundation of Science (CEO Emeritus)
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Fox Foundation for Parkinson's Research National Center for Complementary and Integrative Health National Eye Institute National Institute of Mental Health National Institute of Neurological Disorders and Stroke National Institute on Aging National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse National Institutes of Health Blueprint for Neuroscience Research National Multiple Sclerosis Society National Science Foundation One Mind Pfizer Inc. Sanofi Society for Neuroscience Takeda Pharmaceuticals International, Inc.
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T I M E LI NE 2006 | Establishment | 1st meeting 2014 | SSA Essential Medicines Workshop | 21st meeting | 22nd meeting | 23rd meeting | Dry AMD Workshop | 2007 | Biomarkers Workshop | 2nd meeting | SFN: Neuroscience of Gaming Session Autism and Environment Workshop | 3rd meeting | 4th meeting 2015 | Providing Sustainable Access to Mental Health Care: 2008 | 5th meeting | 6th meeting | Molecules to Mind: Kenya Workshop | Financial Incentives Workshop | Cognitive Grand Challenges Workshop | Venture Philanthropy Strategies Dysfunction in Depression Workshop | Non-Invasive Workshop | 7th meeting Neuromodulation Workshop | Providing Sustainable Access to Mental Health Care: Ghana Workshop | 24th meeting | Assessing 2009 | 8th meeting | Suicidality Workshop | 9th meeting | the Impact of Applications of Digital Health Records on Uganda Workshop | SFN: Social Issues Roundtable | Alzheimer's Disease Research Session | 25th meeting 10th meeting | Animal Law Workshop 2016 | 26th meeting | Neuroscience Trials of the Future 2010 | Sex Differences Workshop | Glutamate Workshop | Workshop | 27th meeting and Multimodal Therapies Workshop | 11th meeting | ICAD 2010 Session | 12th meeting 28th meeting and Development in Absence of Predictive Animal Models Workshop | OECD Workshop 2011 | 13th meeting | Neuroscience and the Law Workshop | AAIC 2011 Session | Animal Regulations Workshop | 2017 | 29th meeting | Biomarkers of Neuroinflammation 14th meeting | 15th meeting Workshop | Blood–Brain Barrier Workshop | 30th meeting | Advancing Therapeutic Development for Pain and Opioid 2012 | 16th meeting | Animal Models Workshop | Use Disorder Workshop Neurodegeneration Workshop | 17th meeting | SSA Human Resources Workshop | Sharing Clinical Research Data 2018 | 31st meeting | Neuroforensics Workshop | 32nd meeting | Workshop | 18th meeting Mobile Technology Workshop | 33rd meeting | Transgenic Neuroscience Research Workshop 2013 | 19th meeting | Accelerating Therapeutic Development Workshop | Meeting on Developing dMRI Standards | 20th meeting
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Foster Relationships and Collaboration By bringing together a diverse group of participants around a particular topic, our activities foster new professional relationships, facilitate cross-sector collaborations, and enable professional development and networking, including the cultivation of new leaders. Inspire New Ideas and Shape the Field Our work can advance and shape the field by framing issues and shining a light on importanttopics, and by generating novel approaches to overcome existing challenges, spurring progress and inspiring action.
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Dzau is and commissioned papers as additional mechanisms president. for informing its membership, other stakeholders, and The three Academies work together as the National Academies of Sciences, the public about emerging issues and matters deserving Engineering, and Medicine to provide independent, objective analysis and scrutiny.
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