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Roundtable on Translating Genomic-Based Research for Health: 2013 Annual Report
Pages 1-12

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From page 1...
... BOARD ON HEALTH SCIENCES POLICY Roundtable on Translating Genomic-Based Research for Health 2013 Annual Report
From page 2...
... Our agenda for 2014 will include further exploration of grand challenges for genomics -- identifying key issues in the evidence evaluation process for genomic technologies, examining pragmatic approaches to educating health care providers about genomics, working with vendors and end users on integrating genomic information into the electronic health record, and developing a framework for investigators and industry to acquire DNA routinely as part of clinical trials. The Roundtable recently welcomed new sponsoring members from the American Academy of Nursing, the Association for Molecular Pathology, the International Society for Cardiovascular Translational Research, the National Institute of Nursing Research, and PhRMA.
From page 3...
... Roundtable Workshops Refining Processes for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests (February 27, 2013) Genome information can identify new drug targets for both common and rare diseases, can identify patients predicted to respond to a specific treatment, and has the potential to significantly reduce the cost of clinical trials by reducing the number of patients that must be enrolled to demonstrate safety and efficacy.
From page 4...
... The goals of the workshop were to articulate and clarify COI policies in the context of the current landscape for medical advancement, examine the impact of COI policies on innovation, and identify best practices to facilitate innovation under the current COI policies while still ensuring scientific integrity and public trust. Stakeholders, including government officials, pharmaceutical company representatives, academic administrators and December 4 Diffusion and Use of Genomic July 11-12 Innovations in Health and Meeting 1 Medicine Workshop ROUNDTABLE TIMELINE 2007 2008 December 5 Meeting 2
From page 5...
... Technological advances and the increasing availability of genomic data and computational systems have resulted in new methods to systematically identify both drug targets and pathways for detecting drugs with a secondary, often seemingly unrelated, indication. The Roundtable hosted a workshop to assess the current landscape of drug repurposing activities in industry, academia, and government; examine enabling tools and technology; and evaluate the business models and economic incentives for drug repurposing programs.
From page 6...
... Roundtable Workshops Assessing Genomic Sequencing Information for Health Care Decision Making (February 3, 2014) The sequencing of the human genome has led to tremendous advances in research and devel opment, increasing our understanding of the basis of disease and hastening genetic-based targeted therapeutic development.
From page 7...
... This greater understanding, combined with the technological advances that have significantly improved genome sequencing accuracy while decreas ing its cost, has led to large-scale sequencing now being used in clinical practice to aid in diagnosis and to identify treatment options for patients. With the expanded use of elec tronic health records (EHRs)
From page 8...
... November 17 July 19 Generating Evidence for Integrating Large-Scale Genomic Diagnostic Test February 22-23 Genomic Information into Development Workshop Meeting 13 Clinical Practice Workshop 2011 November 18 July 20 Meeting 12 Meeting 14
From page 9...
... Currently, this group is focusing its efforts in Oncology: on DNA collection and data generation in clinical Workshop Summary trial designs. March 21 New Paradigms in Drug November 15 Discovery: How Genomic Data July 17-18 October 4-5 Facilitating Development and Are Being Used to Revolutionize Assessing the Sharing Clinical Utilization of Genome-Based the Drug Discovery and Economics of Genomic Research Data Diagnostic Technologies Workshop Development Process Workshop Medicine Workshop Workshop 2012 May 24 November 16 March 22 July 18 Meeting 15 Meeting 16 Evidence for Clinical Utility of Molecular Meeting 17 Diagnostics in Oncology Workshop
From page 10...
... Northrop Grumman Information Systems Director Translational Research February 27 December 3 Refining Processes for Improving the Efficiency the Co-Development of June 24 and Effectiveness Genome-Based Therapeutics Genomics-Enabled of Genomic Science and Companion Diagnostic Drug Repurposing and June 25 December 4-5 Translation Workshop Tests Workshop Repositioning Workshop Meeting 20 Meeting 21 2013 2014 June 5 December 4 February 28 Conflict of Interest and Medical Innovation: Ensuring Integrity Meeting 18 Meeting 19 While Facilitating Innovation in Medical Research Workshop
From page 11...
... PhRMA United States Air Force December 8 February 3 August 18 Facilitating the Integration Assessing Genomic Sequencing Improving Genetics of Genomic Information Information for Health Care Education for Health Care into the Electronic Health Decision Making Workshop Providers Workshop Record Workshop 2015 February 4 August 19 December 9 Meeting 22 Meeting 23 Meeting 24
From page 12...
... The Roundtable explores and implements strategies for improving health through the translation of genomics and genetics research findings into medicine, public health, education, and policy. During the two to three meetings the Roundtable holds each year, specific scientific and policy issues will be identified and discussed that will help further the field of genomics and enable the translation of genomics into health care applications.


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