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2 Overview of the DRI Process
Pages 31-36

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From page 31...
... This concept: • Applies a model based on probability and risk to derive a panel of reference values; • Sets a safe upper intake level to reduce the risk of adverse health effects related to overconsumption of a nutrient; and • Considers the potential role for nutrients or other food substances in reducing the risk of chronic disease. Most of the first DRI values were based on biological indicators related to inadequate intakes of nutrients.
From page 32...
... Such long-term energy intake imbalances are one type of dietary imbalance associated with the risk of chronic diseases. In response, as DRI nutrients have undergone review, the derivation of DRI values has evolved to include consideration of chronic disease risk reduction.
From page 33...
... This includes determining how characteristics unique to a population age/ sex group, such as body size, lifestyle, environment, or other factors, could influence nutrient requirements for that group. This DRI organizing framework provides a systematic approach to deriving the DRIs.
From page 34...
... When evidence is limited and a lack of guidance could have implications for public health, an informed scientific judgment grounded in transparent and judicious documentation becomes necessary. ADAPTING THE DRI ORGANIZING FRAMEWORK TO ENERGY As noted above, the core statistical concept on which the Estimated Average Requirements (EARs)
From page 35...
... . It is also not useful to compare an individual's self-reported energy intake with a calculated expenditure owing to bias in self-reported intake data, as well as the inherent variability in energy expenditure among individuals with similar characteristics.


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