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2 Methodological Approach to the Task
Pages 29-38

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From page 29...
... As part of its evidence-gathering approach, the committee commissioned an update of two systematic reviews of the literature and a de novo systematic review. The committee also gathered and reviewed publicly available information including both original research and systematic reviews from the published peer-reviewed literature, that has become available since the previous study on these topics, Seafood Choices: Balancing Benefits and Risks (IOM, 2007)
From page 30...
... The committee prioritized the list of outcomes to narrow the scope and inform decisions about which exposure–outcome pairs would have sufficient evidence to warrant a systematic review. Protocols for Updated Existing and Conducting De Novo Systematic Reviews The committee appointed a technical expert panel (TEP)
From page 31...
... The committee asked the National Academies' Research Center to carry out the literature search for the updated and the de novo systematic reviews. National Academies staff, working with the committee's consultants, created initial lists of relevant controlled vocabulary terms (Medical Subject Heading [MeSH]
From page 32...
... The PRISMA flow charts for each review are shown in Figures 2-1 and 2-2. 3 For the nutrition reviews updates, there were 12 new articles related to maternal seafood consumption and 4 new articles related to seafood consumption during childhood since the time period covered by the existing systematic reviews.
From page 33...
... The de novo systematic review on associations between contaminants in seafood and health outcomes found 73 included articles. Prior to full data extraction, the Evidence Center conducted a scoping review and extracted high-level data from each included article (see description above)
From page 34...
... SUPPLEMENTARY REVIEW OF SYSTEMATIC REVIEWS In response to the two overarching questions and specific subquestions submitted by the sponsor, the committee was interested in identifying additional health outcomes, toxic elements, and micro-organisms. Those terms not included in the commissioned systematic reviews were searched in a supplementary review of systematic reviews in the published literature.
From page 35...
... The committee was also interested in examining the association between mercury and child health outcomes using studies that did not explicitly report fish or seafood consumption. The search was focused on relevant, timely, and high-quality systematic reviews on mercury exposure during pregnancy, lactation, childhood, or adolescence on child health and development outcomes.
From page 36...
... Mean usual intake and usual intake distributions were estimated for total seafood, seafood groups high and low in long-chain n-3 PUFA, total protein foods (e.g., red meat, processed meat, poultry, eggs, nuts and seeds, legumes, soy) , seafood species, fatty acids, and micronutrients for demographic groups above, and stratified estimates generated by age, sex, race/ethnicity, and income.
From page 37...
... follows the relevant time periods of the life course of the exposed population and the outcome population. The framework was used to guide the committee's discussions, particularly on health outcomes related to nutrient and toxicant exposures through seafood (see Chapter 6)
From page 38...
... USDA Food and Nutrition Service, Center for Nutrition Policy and Promotion, Nutrition Evidence Systematic Review. https://doi.org/10.52570/NESR.DGAC2020.SR0502 (accessed January 30, 2023)


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