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Case Study 40: Community Oubreaks of Asthma Associated with Inhalation of Soybean Dust
Pages 701-706

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From page 701...
... * The following persons were members of the Toxicoepidemiological Committee: Francesc Artigas, Ph.D., Departament de Neuroquirnica, Consell Superior d'Investigacions Cientifiques; Jordi Cami, M.D., Institut Municipal d'lnvestigaci6 Medica; Josep Caixach, Ph.D., Laboratori d'Espectrometria de Masses, Consell Superior d'lnvestigacions Cientifiques; Anna Galbe, M.D., Departament d'Epidemiologia, Institut Municipal d'lnvestigaci6 Medica; Xavier Guardino, Ph.D., Institut Nacional de Seguretat i Higiene en el Treball; Guillem Massague, Ph.D., Corporacio Metropolitana de Barcelona; Perran Morell, M.D., Secci6 d'Aparell Respirator, Hospital Vall d'Hebron; Carles Munllo, Ph.D., Departament d'Econometria, Facultat d'Econdmiques, Universitat de Barcelona; Antoni Plasencia, M.D., Servei d'Epidemiologia i Estadistiques Vitals, Institut Municipal de la Salut; Josep Roca, M.D., Servei de Pneumologia, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona; Andreu Segura, M.D., Departament de Sanitat i Seguretat Social, Generalitat de Catalunya; Jordi Segura, Ph.D., Depaltament de Farmacologia i Toxicologia, Institut Municipal d'lnvestigaci6 Medical and Juan Seoane-Carnba, Ph.D., Departament de Monica, Facultat de Farmicia, Universitat de Barcelona.
From page 702...
... 23 ~eteoml~c inmate _ Elects on epidemic days ham Our swoons ~a~5^~~ soutb~est. PI ^nsIYsls For each product unloaded, a risk ratio was Calculated between me pm~Nli~ ~ an =~_ Memo ~ me dam when me Paul was being unloaded and the probability of an epidemic on the days ~_~ _~ConAdence inte~als ~r tbe risk ratios we~ estimated by tbe ~~.~_~ by-two table, the lower limit of the confidence interval was ~lculat~a~~ null hypothesis was also tested with Fisber's exact test.26 Evalua~-e~t~ asthma epidemics, with control Or the other products, were cards out with use of the ~anteLHacnszel metb~.27 IS Thirteen of 23 "unusual asthma days" lden11Red during 1be study period had hourly duster patterns EON EDICT
From page 703...
... The daytime wind patterns remained constant throughout the epidemics, characterized by mild southeasterly to southwesterly winds (less than 5 m per second on all epidemic days except for one day on which the maximal speed was 6.1 m per second)
From page 704...
... it did not have bag filters installed in the cyclone dust-collection system, thereby allowing the release of large amounts of soybean dust into the air. High barometric pressure and low southeasterly to southwesterly wind speeds were registered on epidemic days appropriate weather conditions for moving air from the harbor to the city.
From page 705...
... Only castor-bean dust has been reported to be specifically causative of asthma epidemics.~~'° In New Orleans, the marked decline in asthma outbreaks has recently been attributed both to better socioeconomic conditions and the availability of better medical care for indigent patients with asthma, rather than to the disappearance of specific allergens or industrial chemical pollutants." In New York City, asthma-epidemic days were more likely to occur when susceptible persons spent more time indoors, suggesting an exposure to agents in the home.28 No relation was found, however, between outdoor air pollution and outbreaks of asthma,36 as in Barcelona. In Birmingham, a large asthma outbreak appeared to be caused by D2dimella ex~t~alis,5 but a more recent study could not confirm this hypothesis,37 and the question of the origin of the epidemic remains open.38 Soybeans have been identified as causing bronchial asthma, although infrequently so.
From page 706...
... Time and space clusters on unusual asthma days in Barcelona. In: Proceedings and abstracts of the 11th Scientific Meeting of the International Epidemiologic Association, Helsinki, August 8-13, 1987.


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