Isotopes for Medicine and the Life Sciences (1995) / Chapter Skim
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EXECUTIVE SUMMARY
EXECUTIVE SUMMARY
Pages 1-8
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One of every three hospitalized patients in the United States undergoes a nuclear medicine procedure, with a total value estimated at $7 billion to $10 billion per year. More than 36,000 diagnostic medical procedures that employ radioactive isotopes are performed daily in the United States, and close to 100 million laboratory tests that use radioactive isotopes are performed each year.
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The nuclear medicine community in particular has been highly vocal in its concern that the needs of the various users in the United States will not be adequately met in a future market controlled by one or two foreign sources and have suggested that DOE fund a new accelerator facility with production of isotopes as its primary mission, a National Biomedical Tracer Facility (NBTF)
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In the near term this means that the electromagnetic separation capabilities of the Oak Ridge National Laboratory calutrons should be maintained in standby mode until a more cost-effective source of enriched stable isotopes can be developed or external sources fail to meet demand. If a more costeffective technology does not emerge within 5 years, subsidized operation of the calutrons should be resumed (Recommendation 1, Chapter 2~.
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Radiopharmaceutical companies state that the present domestic and foreign suppliers are reliable and that they have or soon will sign long-term supply contracts with existing producers. In view of the demonstrated reliability of the current sources of commercially valuable isotopes and their steps to secure adequate backup, the committee recommends that the Omega West reactor at Los Alamos National Laboratory or reactors at other facilities NOT be reopened as a dedicated source of molybdenum-99 and other reactorproduced isotopes (Recommendation 1, Chapter 3~.
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An NBTF that can incorporate the production facilities with the necessary infrastructure for research and training in isotope production and related activities is essential for the United States to maintain continued leadership in biomedical research using radiotracers. The choice between cyclotron and linac is beyond the scope and expertise of this committee report, but an accelerator with an energy of 80 MeV would be sufficient for preparation all of the radionuclides envisioned for current and future use.
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In the United States, a healthy set of partnerships exists between national laboratories and universities, primarily involving research. Successful partnerships between national laboratories and industries in research and development have also been established (the cooperative research and development agreement mechanism)
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A NATIONAL ISOTOPE POLICY On the basis of its congressional mandate, its historic role, and its technical resources and expertise, DOE has important roles to play in all aspects of isotope production, research, and education. Although the full cost recovery provision of the Energy and Water Development Appropriations Act of 1990 (Public Law 101-101)
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From page 8... ...
This National Isotope Program Advisory Committee should also provide advice on the development and execution of the several educational programs associated with isotope production and use (Recommendation 2, Chapter 61.
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