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(NAS Colloquium) Genetics and the Origin of Species From Darwin to Molecular Biology 60 Years After Dobzhansky (1997) / Chapter Skim
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Evolution by the birth-and-death process in multigene families of the vertebrate immune system
Pages 109-116

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 109...
... ma. Concertedcr~[udon~asalsoi~kedto ~plainthed~c~i~ and Solute of the mcl~lt:igene families offeror bistocompatib~i~ comply (SHE)
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From page 111...
... We Shave fierce construct~d~phylogenedc traces far human class ll~ and genes separately Fig. i shows 1hc Bee IF HISS 11 ~ Bcnes mom tbrcc polymorphic loci a.
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From page 112...
... 4~. This indicates 1~1 far ~laliv~ly closed related o~n~ms brand loci maintain their Ninety identity despite ibe appoint ~cur~n~e of repeated gene dup~c~ion and that no or i:n~tcllocus~elletico=~han~es~haveocc~ul,qd~:mon~diEtIelltloc~i.
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From page 113...
... C<~llogoTum lS>aper:~Nci~/.
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From page 114...
... pigs, and rabbits, which arc all d<>m~stic~ted animals. Particularly in1oresdrg are the ca1Uc and sheep gene clusters Limb belong to group B
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From page 115...
... However, heyhavenotdoncanys1~t~istic~IlestoF:ll~Je~l~icclusters,andit seemsthatthis iIllc~rnlin~ling of~llclosir<>m di~f~r~nllociwas causedbystocb~ticors~mpling~n~r~{course.therarea~ dcar-cutc~scsof~n ~hanyesb~t~cndib~rent~IlCloci (I3,66~.bu1theircontr~utionto M HC ~nc diverge scemsto \~(# BIrtb-and-Dealh ~odelofE\olulion.Inthismodelofevolu~ tiOll. d~lplical~gc~lesareprodtlced ~ variousmcc~hallisl~sill~ Eluding tandem and block gene duplication.
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From page 116...
... 73) suggested that 1bese dosed related sequences are sump ~ German ~ ~ ~ somatic Bane conversion.
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Key Terms

  • gene duplication
  • gene families
  • repeated gene
  • somatic gene
  • evolutionary pattern

  • gene cluster
  • polymorphic loci
  • vertebrate species
  • deleterious mutations
  • sequence data

  • human class
  • various vertebrate
  • poorly expressed
  • gene clusters
  • gene turnover

  • related genes
  • dna sequence
  • bootstrap value
  • sequence similarity
  • functional gene

  • genes subsequently
  • alleles exist
  • allelic sequences
  • tandem gene
  • world monkey

  • lend support
  • block gene
  • genus names
  • repeated tandem
  • sheep gene


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