Biomedical Models and Resources Current Needs and Future Opportunities (1998) / Chapter Skim
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2. Biomedical Model Definition
2. Biomedical Model Definition
Pages 10-11
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A biomedical model is a surrogate for a human being, or a human biologic system, that can be used to understand normal and abnormal function from gene to phenotype and to provide a basis for preventive or therapeutic intervention in human diseases. For example, characterization of mouse models of various dwarfing syndromes, cloning of mutated genes, and parallel comparative genetic mapping and cloning of genes for similar human syndromes have led to an understanding of various human dwarfing conditions and have suggested therapies based on biologic knowledge, rather than shotgun testing.
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From page 11... ...
are universally used by the scientific community, including those using animal models. in vitro models provide important perspectives on the continuum of biologic processes that ultimately must be investigated at the organismal level.
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