The Children's Vaccine Initiative Continuing Activities (1995) / Chapter Skim
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DETERMINING VACCINE NEED
DETERMINING VACCINE NEED
Pages 5-7
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From page 5... ...
The rather unexpected results of a disease surveillance study in Cairo, Egypt, illustrate this last point. During this recent 18-month project, investigators collected blood and nasopharyngeal samples from 1,635 preschool children admitted with pneumonia to two of the city's communicable diseases hospitals.
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From page 6... ...
influence were infected with nontypeable organisms.4 In addition, there is some evidence suggesting that nonencapsulated Hib strains can be responsible for serious disease in older children.5 These and other similar data suggest that in certain settings, a conjugate Hib vaccine is likely to prevent only a moderate proportion of Haemophilus disease. Given the relative high cost of such vaccines, these data argue strongly for further epidemiologic testing to determine the prevalence of Haemophilus types in settings in which immunization programs are being contemplated.
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From page 7... ...
pneumonias, and preliminary subtyping indicates types 1 and 5 are the most common on the subcontinent. Data gathered over the past several years from Pakistan, Bangladesh, and India indicate that, compared with the United States, pneumococcal disease disproportionately strikes the very young, those less than 5 months old.
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