Review of the U.S. Naval Medical Research Institute's Toxicology Program (1994) / Chapter Skim
Currently Skimming:
4 EVALUATION OF THE PRELIMINARY 10-YEAR STRATEGIC PLAN OF THE TOXICOLOGY DETACHMENT
4 EVALUATION OF THE PRELIMINARY 10-YEAR STRATEGIC PLAN OF THE TOXICOLOGY DETACHMENT
Pages 29-36
The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.
From page 29... ...
Less emphasis was placed on basic research than on applied research; emphasis was placed on various degrees of applications issues or methods. In addition to providing the research-planning document, NMRITD personnel made presentations and provided an outline regarding future program direction.
|
From page 30... ...
4. What role should basic research play in the overall toxicology program to be executed at NMRITD, as compared with the current emphasis on applied research?
|
From page 31... ...
The specialists should interface with others in academia, government agencies, and industry where new methods are being developed. Basic research could be bolstered through external contracts.
|
From page 32... ...
There is also a need for mechanistic toxicological research programs; these programs should focus on advancing scientific understanding of those broad toxicological issues that are deemed to have the most impact on the Navy's needs. The basic research programs should address issues that might be confidential or specific to the Navy, such as exposure to chemicals under hyperbaric conditions.
|
From page 33... ...
The mission implies that a greater emphasis should be placed on toxicity characterization than on basic research. The emphasis on descriptive toxicology is based on the fact that much of the data currently required for health-hazard analysis and risk assessment are obtained through classical toxicological experimentation, even though such work is often considered basic research.
|
From page 34... ...
There is a need for actual basic research programs, but such investigations should address issues that are confidential or needs that are specific to the Navy. The subcommittee recommends that the major emphasis should be on applied toxicological research as it relates directly to the environmental and occupational health needs of the Navy.
|
From page 35... ...
~ The Navy's process for acceptance of proposals and for funding should dictate the mix of applied and basic research studies as defined by immediate and tong-range needs. · Annual review of the research plan with the best projections of need on a multiyear basis is a good practice for maintaining efficiency, ensuring scientific focus, and keeping costs at a minimum.
|
From page 36... ...
36 The virulence factors of Campylobacter that are important during infection of people are also unknown. We have a collection of putatively virulent and avirulent isolates that will be characterized in vitro and in vivo to acquire data on potentially relevant factors.
|
Key Terms
This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
More
information on Chapter Skim is available.