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Pages 69-73

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From page 69...
... Site Contents Web address (URL) Mouse Genome Database MRCa Mammalian Genetics Unit Mapping data (all techniques)
From page 70...
... 1996. Genetic composition of the recombinant congenic strains.
From page 71...
... And that is the basis for my concern today. CHANGE IN LABORATORY ANIMAL SCIENCE The change has occurred over the last 10 to 15 years and mainly over the last 5 to 10 years.
From page 72...
... Such standardization is one aspect of this global drug development plan that has an impact on the use of animals. SEGMENTATION OF TOXICOLOGY TESTING Another aspect of globalized pharmaceutical development is the segmentation of toxicology testing.
From page 73...
... Another reason is that most pharmaceutical development strategy uses rats as the rodents and dogs as the nonrodents. Because these companies develop a large database on the effects of the pharmaceutical on the rat during their testing, they want to be able to use that information in test approach selection, dose selection, and interpretation of results.


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