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Fluid Resuscitation State of the Science for Treating Combat Casualties and Civilian Injuries (1999) / Chapter Skim
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Executive Summary
Pages 1-8

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From page 1...
... Because of these and other concerns, the Office of Naval Research asked the Institute of Medicine to provide an independent assessment of the current status of resuscitation fluids and resuscitation protocols for combat casualties and to develop a series of findings and recommendations for fi! ture research directed at the acute treatment of massive blood loss on the battlefield.
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From page 2...
... Such fluids should address the metabolic and cellular consequences of traumatic shock and the potential disadvantages of existing fluid formulations. Future research directed at acute treatment of massive blood loss on the battlefield should explore the development of an improved resuscitation fluid.
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From page 3...
... Clinical research specifically has been hampered by He lack of an organized national approach to trauma research that takes advantage of He considerable clinical material and research expertise among the regional trauma centers. Furthermore, approaches to bow current Reagent and future research are hampered by inadequate methods for classification of the severity of clinical trauma; such classifications are essential to evaluations of the efficacies of new ~eatment protocols that involve modifications In fluid formulations or novel therapies.
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From page 4...
... Finally, the complex events that result from the initial insult, tissue injury, and resuscitative attempts provide numerous potential therapeutic targets for novel interventions. Novel therapeutic strategies might be conveniently, if somewhat artificially, categorized as those that prevent the early complications of the shock syndrome (prevention)
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From page 7...
... ~ ~ ~ .~ ~ ~ ~ If: : :::: ~-~ ~ ~ ~ :~ ~.:~:~:~ ~-~ ~:~ ~:~ ~ ~ ~ ~ ~:~ ~ ~ ~ :: air: :: :. i::: :~ ~ ~:~ ~:~ :: ~ ~:~ ~:~ :~:::~:~:Any~:a~nd~:a~ll :~a:nimal:~resea~rch~ ~:~shou~ld~be~co~nd~ed~:n~: acco~rda~n~ce~:-w'th~:~:th~e~ ~:~ :: :: ~ : Guide ~r:~e~m andante of lLabora~g<~Ar7rmals~ (bJR~C~199~63 ~ ~ ~ ~ ~ :~: ~ ~:~ ~ ~ ~ ~ Aid: ~''~;: = j~.~ :~ ~ Owl Selected ~topi~cs~::~a:t~:~-exisi:ing~ regional trauma ~ Hi so :Federal agencies ~ :~: U S
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Key Terms

  • resuscitation fluids
  • clinical trials
  • hemorrhagic shock
  • battlefield casualties
  • existing lactated

  • blood loss
  • adequate control
  • hypertonic saline
  • trauma centers
  • regional trauma

  • massive blood
  • traumatic shock
  • battlefield casualty
  • cellular consequences
  • implement clinical

  • existing regional
  • resuscitation fluid
  • acute treatment
  • fluid formulations
  • accompanies hemorrhage

  • research involving
  • tissue injury
  • multicenter clinical
  • including multicenter
  • initial fluid

  • involving modifications
  • resuscitation research
  • animal models
  • injured combatants
  • clinical trauma


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