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Submarine Exposure Guidance Levels for Selected Hydrofluorocarbons HFC-236fa, HFC-23,and HFC-404a (2000) / Chapter Skim
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Pages 25-25

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From page 25...
... reported reduced weight gain and decrements in alerting response in the dams at 20,000 ppm, the same concentration as the NOAEL identified inthe 14-week toxicity study. Because the purpose ofthis project was to establish exposure guidance levels for use on submarines, vessels that have no female crew members, the subcommittee ciid not use the developmental toxicity study as the basis for calculating the 24-hr EEGL or 90ciay CEGL.
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Key Terms

  • maternal toxicity
  • guidance levels
  • exposure guidance
  • toxicity study
  • developmental toxicity

  • alerting response
  • guidance level
  • transient decrements
  • female crew
  • day cegl


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