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Methods for Developing Spacecraft Water Exposure Guidelines (2000) / Chapter Skim
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5 Ranking Spacecraft Contaminants for Risk Assessment
Pages 108-114

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From page 108...
... Sewing priorities for risk assessment is a separate function from conducting risk assessments, which in turn is a separate function from making risk management decisions. There are insufficient resources to conduct formal risk assessments on ah potential water contaminants, so priorities must be established among them.
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From page 109...
... The decision makers would make subjective, quaTitadve, and, presumably, wise decisions. The parameters or the data elements upon which candidates would be chosen would not be specified, nor would chemical candidates competing for a formal risk assessment be weighed against each other in a quantitative sense.
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From page 110...
... Formal System with Parameters, Weights, and Interrelationships Specified In a formal system, priorities would be based on a specified set of parameters, a formula would be developed that combines scores for the various parameters, and the relationship and weighting of the parameters would be specified. The formula could be as simple as the sum of scores of various parameters or a more complex formula in which parameters are given unequal weights and their relationship would be other than additive.
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From page 111...
... Design requirements: The physical design of the spacecraft should be a major consideration in the selection of chemical candidates for risk assessment. A primary concern is the effectiveness of systems in producing or limiting exposure in the spacecraft to specified levels.
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From page 112...
... It could be that the timing of the design phase will in part force selection of chemical species for formal risk assessment. Once the design is completed, and later when the system is built, the system's capacity for controlling and eliminating exposures should determine the choice and use of candidate chemicals during flight.
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From page 113...
... Pp. 91-103 in Chemical Risk Assessment and Occupational Health: Current Applications, Limitations, and Future Prospects, C
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From page 114...
... METHODS FOR DEVELOPING SPACECRAFT WATER EXPOSURE GUIDELINES 0.9 0.8 0.7 0.6._ Q Q o cat 0.50.4 0.3 0.2 .P(d)
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Key Terms

  • formal risk
  • candidate chemicals
  • risk assessments
  • chemical candidates
  • chemical species

  • choosing candidates
  • complex mixtures
  • mixtures recommended
  • separate function
  • hoc approach

  • carcinogenicity testing
  • physical design
  • quantitative sense
  • quantitative risk
  • limit value

  • hazardous substances
  • routine operations
  • industrial hygienists
  • sensitivity analysis
  • force selection

  • expert decision
  • factors specified
  • major consideration
  • carcinogenic hazards
  • design phase

  • iarc monographs
  • requires collecting
  • permissible lifetime
  • increasing formality
  • conduct risk


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