Phthalates and Cumulative Risk Assessment

The Task Ahead

Status: Available Now

Size: 208 pages, 6 x 9

Publication Year:2008

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PAPERBACK ISBN-10: 0-309-12841-2 ISBN-13: 978-0-309-12841-4	$46.00	Add to Cart

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Authors:
Committee on the Health Risks of Phthalates, National Research Council
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Table of Contents
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Front Matter	i-xx
Summary	1-12	(skim)
1 Introduction	13-20	(skim)
2 Phthalate Exposure Assessment in Humans	21-38	(skim)
3 Toxicity Assessment	39-67	(skim)
4 Current Practice in Risk Assessment and Cumulative Risk Assessment	68-105	(skim)
5 Cumulative Risk Assessment of Phthalates and Related Chemicals	106-137	(skim)
6 Data Gaps and Research Needs	138-140	(skim)
Appendix A: Statement of Task	141-141	(skim)
Appendix B: Biographic Information on the Committee on Health Risks of Phthalates	142-146	(skim)
Appendix C: Analysis of a Mixture of Five Phthalates: A Case Study	147-159	(skim)
Appendix D: Evaluating Multiple End Points Simultaneously in a Mixture of Three Antiandrogens: A Case Study	160-188	(skim)

Description

People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals.
Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.

Phthalates and Cumulative Risk Assessment

The Task Ahead

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