The Science and Applications of Microbial Genomics: Workshop Summary
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  • Status: Final Book
  • ISBN: 978-0-309-26819-6
  • 403 pages
  • Downloads: 1,777
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Overview

Authors

Description

Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial world around us.

On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.

Topics

  • Biology and Life Sciences — Genetics
  • Health and Medicine — Other Diseases
  • Biology and Life Sciences — Biology
Contents

Table of Contents

skim chapter
Front Matter i-xxiv
Workshop Overview 1-116
Appendix A 117-378
Appendix B--Agenda 379-382
Appendix C--Acronyms 383-386
Appendix D--Glossary 387-394
Appendix E--Speaker Biographies 395-404
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Suggested Citation

Institute of Medicine. The Science and Applications of Microbial Genomics: Workshop Summary. Washington, DC: The National Academies Press, 2013.

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