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Appendix D--Glossary
Pages 387-394

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From page 387...
... or ligase chain reactions (LCRs) , as well as by natural gene duplication.
From page 388...
... : Any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases that project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei. Duplicate read inferred sequencing error estimation (DRISEE)
From page 389...
... and in medicine and genetics as a research organism and that occurs in various strains that may live as harmless inhabitants of the human lower intestine or may produce a toxin causing intestinal illness. Genetic fingerprinting: A method employed to determine differences in amino acid sequences between related proteins; relies upon the presence of a simple tandem-repetitive sequences that are scattered throughout the human genome.
From page 390...
... : The name given to treatment regimens that aggressively suppress HIV replication and progression of HIV disease. The usual HAART regimen combines three or more anti-HIV drugs from at least two different classes.
From page 391...
... Metagenomics Rapid Annotation using Subsystem Technology server (MGRAST) : A community resource providing an automated analysis platform for metagenomes providing quantitative insights into microbial populations based on sequence data.
From page 392...
... RNA (ribonucleic acid) : Any of various nucleic acids that contain ribose and uracil as structural components and are associated with the control of cellular chemical activities.
From page 393...
... : A DNA sequence variation occurring when a single nucleotide -- A, T, C, or G -- in the genome (or other shared sequence) differs between members of a biological species or paired chromosomes in an individual.
From page 394...
... Whole genome sequencing: A laboratory process that determines the complete DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast.


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