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Calculating the Secrets of Life Contributions of the Mathematical Sciences to Molecular Biology (1995) / Chapter Skim
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Pages 106-107

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From page 106...
... It is possible that the hy-pothesis of common origin is correct and that so much evolutionary change has taken place that no significant similarity remains. The next section, "Two Behaviors Suffice," examines the results of this search for unusual similarity using more subtle sequence comparison algorithms.
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From page 107...
... Hearing Distant Echos Table 4.1 Exact Match P-Values tRNA GenBank Length Hn 1 - e-&n b~ Locus (n) ala-la ECOTRA1A 76 9 0.26 1.87x 10-5 ala-lb ECOTRA1B 76 9 0.26 1.87x 10-5 cys ECOTRC 74 8 0.69 2.67x 10-4 asp-1 ECOTRD1 77 8 0.71 2.79x 104 glu-1 ECOTRE1 76 10 0.71 1.25x 10-6 glu-2 ECOTRE2 76 10 0.71 1.25x 10-6 phe ECOTRF 76 9 0.26 1.87x 10-5 gly-1 ECOTRG1 74 7 0.99 3.90x 10-3 gly-2 ECOTRG2 75 6 1.00 5.70x 10-2 gly-3 ECOTRG3 76 9 0.26 1.87x 10-s his-1 ECOTRH1 77 9 0.26 1.89x 10-5 ire-1 ECOTR11 77 9 0.26 1.89x 10-5 ire-2 ECOTRI2 76 10 0.71 1.25x 10-6 lys ECOTRK 76 6 1.00 5.78x 10-2 leu-1 ECOTRL1 87 8 0.76 3.19x 10-4 leu-2 ECOTRL2 87 8 0.76 3.19x 104 leu-5 ECOTRL5 87 9 0.29 2.16x 10-5 met-f ECOTRMF 77 9 0.26 1.89x 10-5 met-m ECOTRMM 77 8 0.71 2.79x 10-4 asn ECOTRN 76 7 0.99 4.01 x 10-3 gin-1 ECOTRQ1 75 8 0.70 2.71 x 10-4 gin-2 ECOTRQ2 75 8 0.70 2.71 x 104 erg-1 ECOTRR1 76 7 0.99 4.01 x 10-3 erg-2 ECOTRR2 77 7 0.99 4.07x 10-3 ser-1 ECOTRS1 88 8 0.76 3.23x 104 ser-3 ECOTRS3 93 9 0.31 2.33 x 10-5 thr-ggt ECOTRTACU 76 7 0.99 4.01 x 10-3 val-1 ECOTRV1 76 8 0.70 2.75x 104 val-2a ECOTRV2A 77 8 0.71 2.79x 104 val-2b ECOTRV2B 77 9 0.26 1.89x 10-5 trp ECOTRW 76 7 0.99 4.01 x 10-3 tyr-1 ECOTRY1 85 8 0.75 3.11 x 10-4 tyr-2 ECOTRY2 85 8 0.75 3.11 x 104 Hn' the length of the longest exact match between the listed tRNA molecule and a 16S rRNA molecule; 1- e ~ the p-value (estimate of signiblcance)
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Key Terms

  • sequence comparison


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