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Calculating the Secrets of Life Contributions of the Mathematical Sciences to Molecular Biology (1995) / Chapter Skim
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Pages 127-129

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From page 127...
... given by the Ewens sampling formula (5.4) does indeed satisfy equations (5.10)
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From page 128...
... For the pynmidine data, there are 21 segregating sites, giving an approximate 95 percent confidence interval for O of 4.46 + 3.10 . This should be compared to the estimate of 10.62 + 6.29 obtained Tom the Ewens sampling formula.
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From page 129...
... The nodes in the tree represent the mutations that have generated the segregating sites, and the tips represent the sequences. A convenient algorithm for finding these trees is provided by Griffiths (1987)
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Key Terms

  • segregating sites
  • ewens sampling
  • sampling formula
  • mutation occurs
  • dna sequence

  • dna sequences
  • data described


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