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Calculating the Secrets of Life Contributions of the Mathematical Sciences to Molecular Biology (1995) / Chapter Skim
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Pages 130-131

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From page 130...
... The corresponding theory of the uprooted genealogical trees that arise when the ancestral labeling is unknown has recently been developed by Griffiths and Tavare (1994c3, and this reacts to a practical computationaLmethod for estimating Oby maximum likelihood. Our analysis of the mitochondrial data set has shown that while parts of the region are consistent with a simple evolutionary model, there are sites which are behaving in a more complicated way.
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From page 131...
... satisfying ~ Q=O, >,K=1~ j = 1, and if the common ancestor of the sample has distribution it, then the distribution of a gene at any point in the tree is also a, and the process is stationary. From the data analyst's perspective, the sample of n genes can be sorted into a vector N -- (N1, N2 ~ .
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Key Terms

  • common ancestor
  • mutation occurs
  • mitochondrial data
  • maximum likelihood


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