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Pages 230-231

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From page 230...
... E cold contains circular duplex DNA molecules.
From page 231...
... of the parasite trypanosome forms a link of some 5,000 to 10,000 unknotted DNA circles the DNA equivalent of chain mail (Marini et al., 1980; Englund et al., 1982; Rauch et al., 1994~. Work is ongoing (Rauch et al., 19943 in which the topological structure of kDNA is being studied by means of partial digest of the network, electrophoresis, and electron microscopy of the characteristic fragments, in which the large kDNA link is being randomly broken up into small sublinks, and the frequency of occurrence of these sublink units is being used (statistically)


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