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Pages 5-6

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From page 5...
... Predicting the folded structure of a protein from the amino acid sequence remains an extremely challenging problem in mathematical optimization. The challenge is created by the combinatorial explosion of plausible shapes, each of which represents a local minimum of a complicated nonconvex function of which the global minimum is sought.
From page 6...
... 6 CALCULATING THE SECRETS OF LIFE F: O Ax cad a , .


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