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Infectious Diseases of Mice and Rats (1991)

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Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
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INDEX

A

Abdominal enlargement, 260

hemopoietic system infections, 219

multiple system infections, 238

Abortions and stillbirths. 178, 260

Abscesses, 45, 49, 176, 178, 189, 260, 266

cervical, 74, 76, 189

face, orbits, and tail, 183-184

kidneys, 56, 74

liver, 56, 76, 129

lung, 45, 49

Adenovirus, 10, 123-126, 194

Age factors

digestive diseases, 85, 86, 93, 96, 99, 105, 107, 112-113, 117, 148 , 158

hemopoietic system infections, 201, 209, 213

multiple system infections, 238-239, 249

respiratory infections, 48, 83, 102

Agents (characterization)

central nervous system infections, 223. 227

definition of term, 32

digestive system infections, 86, 87, 91, 94-95, 98, 103-104, 112, 116-117, 119-120, 123-124, 127-128, 132-133, 139-140, 142, 146, 151 , 156-157, 159, 160, 162

genitourinary system infections. 232, 234

hemopoietic system infections. 199-200, 206, 212, 215, 218

multiple systems infections, 237, 241, 244, 248, 252-253

respiratory system infections, 36, 43-44. 48-49. 51-52, 54-55. 59, 62, 65-66, 70. 72, 73. 75. 77-78, 80. 81-82

skin and joint infections, 166-167, 172, 174-175, 177, 182-183, 186 , 188. 190, 192

see also Bacterial infections (agent characterization);

Viral agents;

Zoonotic agents

Airflow systems, general, 19-20

Alopecia, see Dermatitis and alopecia

Amputations, 164, 169, 172, 178, 197. 260

Amyloidosis, 181, 266

Anemia, 178. 211, 212, 213, 214, 263, 266

Ankylosis. 178, 266

Anorexia. 56. 172, 260

Arthritis, 11, 45. 47. 56. 94, 158, 164, 165, 173-176, 178, 266

Ascites, 123, 201. 211. 228, 247. 267

Aspicularis tetraptera, 159-160

Ataxia, 238, 260

Atelectasis. 83, 267

Athymic (nu/nu) mice, immune response, 260-261

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

B

Bacillus piliformis, 12, 86, 126-131

Bacterial infections (agent characterization)

arthritis, 165

barrier systems, 19, 20

digestive system infections, 126, 127-128, 131-132, 139-140, 142

genitourinary system infections, 232, 234

hemopoietic system infections, 212, 215

prevalence, general, 10, 11-12

respiratory. 43-44. 48-49, 51, 55, 62, 70, 72, 73, 75, 77-78, 80

skin and joint infections, 174-175, 177, 181, 182-183, 188

tests for. 22-24

see also specific agents

Barbering, 196

Barrier techniques, 5, 6, 14-15, 17-20

central nervous system infections, 223, 226

digestive system infections. 109, 126, 138, 146, 150, 153

multiple system infections, 240, 246, 251

respiratory infections, 41, 47, 54, 61, 79, 81

skin and joint infections, 178-179

Behavioral trauma. 182, 195-197, 207

chattering (mice), 37, 44, 70, 261

circling and rolling, 143, 224, 261

hyperexcitability, 224, 263

reluctance to move, 44, 49, 70. 129, 134, 149, 201, 264

self-mutilation, 184, 185, 195

Birth weight reduced, 38, 134, 261

Biting, 195-196, 207

Bordetella bronchiseptica, 35

Brain, 78, 106, 107, 202, 228, 229, 238, 239, 246, 250, 267

Breeding, 13-16, 17-20

digestive system infections, 97, 99, 101

multiple system infections, 240

respiratory infections, 47

see also Cesarean derivation

Bronchiectasis and bronchiolectasis, 42, 45, 49, 267

C

Cages, general, 20

Canada, 7-8, 9, 10

Carcinogenesis/spontaneous neoplasia

digestive system, 140, 141

hemopoietic system infections, 79. 171, 205-206, 217-221

leukemia, 79, 171, 205, 217-221, 240, 243, 245, 246, 247, 270

mammary glands, 192-195

multiple systems infections. 242, 247, 250

respiratory system, 47

salivary glands, 249

skin and joint infections, 192

Cell/tissue cultures, 22. 24, 276

central nervous system infections, 227

digestive system infections. 93, 101. 107, 122, 123, 137

genitourinary system infections, 232

hemopoietic system infections, 204. 206, 210-211

multiple system infections. 238, 244, 248, 250

prevalence data and, 11-12

respiratory infections, 40, 46, 48, 53, 57, 64, 71, 74, 79, 81, 82

skin and joint infections, 176, 183. 187, 203-204

Central nervous system infections. 222-230

agents, 223, 227

clinical signs, 224, 228

control225-226, 229

diagnosis, 225, 229

epizootiology, 223-224, 227-228

hosts, 223, 227

pathology, 224-225, 228-229

research history/prevalence, 222-223, 226-227, 237, 241

research interference, 226, 229-230

see also Brain;

specific agents

Cervical edema, 99, 261

Cesarean derivation

central nervous system infections, 226

digestive system infections, 92, 102, 109, 115, 126, 128, 129, 131 , 138, 144, 146, 150, 153

genitourinary system infections, 233

hemopoietic system infections, 204, 213, 216

multiple systems infections, 246, 251

respiratory infections, 46, 50, 54, 58, 61, 69, 77, 79, 81, 83

skin and joint infections, 170, 175, 177, 178, 181, 186, 187, 190

Chattering (mice), 37, 44, 70, 261

Chlamydia psittaci, 35, 72

Chlamydia trachomatis, 35, 69-72, 188

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

Cilia-associated respiratory bacillus (CAR), 34. 38, 48-50

Circling and rolling, 143, 224, 261

Citrobacter freundii. 86, 139-141

Clinical signs, 259-265

central nervous system infections, 224, 228

definition of term, 32

digestive system infections, 88, 92, 95, 99-100, 105, 113. 117, 121 , 125, 129, 134, 140, 143, 149, 152, 155, 157, 160, 161, 163

genitourinary system infections, 189, 233, 234

hemopoietic system infections, 201-202, 207, 212, 215, 219

multiple systems infections. 238, 242, 245, 249, 254-255

respiratory system infections, 37-38, 44, 49, 52, 56, 60, 63, 66, 70, 72, 74, 76, 78, 80, 82, 172, 189

skin and joint infections, 168, 172-173, 175, 178, 180, 183-184, 186, 188, 193

Colon and cecum, 107, 129, 130, 139, 140-141, 157, 158, 159, 161, 162, 163, 249, 267

Complement fixation (CF)

central nervous system infections, 229

digestive system infections, 88, 89, 95, 96, 100, 108, 122, 126, 128

multiple system infections, 241, 243, 246

Conjunctivitis, 78, 80, 97, 99, 134, 178, 189, 261

Control techniques

central nervous system infections, 225-226, 229

definition of term, 32

digestive system infections, 90, 93-94, 97, 101-102, 103, 106, 115-116 , 118, 122

genitourinary system infections, 233, 235

hemopoietic system infections, 204, 209-210, 213, 216, 221

multiple systems infections, 240, 243, 246, 251-252, 256

respiratory system infections, 40-41, 46-47, 50, 54, 58, 61, 64, 69, 71, 72, 75, 77, 79, 81, 83

skin and joint infections, 170-171, 173, 176, 178-179, 181, 185, 187, 190, 191, 194

see also Barrier techniques;

Cesarean derivation;

Monitoring and monitored animals;

Vaccination

Conventional animal, defined, 9

Convulsions, 224, 261

Corneal ulceration, 99. 261

Corynebacterium kutscheri.11-12. 34, 35. 54-58, 164, 178

Cutaneous papules, 191, 267

Cyanosis, 66, 70, 178, 238, 261

Cytomegalovirus, 87-94

D

Dacryoadenitis, 189

Deaths, high and low mortality, 261-262

central nervous system infections, 224

digestive system infections, 105, 131. 140, 143

hemopoietic system infections, 201

skin and joint infections, 168, 172, 178, 179

Defined flora, 6, 9

Definitional issues, see Terminology

Dehydration, see Diarrhea

Demyelination and remyelination, 223, 225, 250, 267

Dermatitis and alopecia, 164. 262

infectious agents, 180, 181, 182, 183, 186, 191

noninfectious causes, 195-197

Dermatophytes, 185-187

Diabetes, 145, 205

Diagnosis, 259-274

central nervous system infections, 225, 229

definition of term, 32

differential diagnosis, 195-197

digestive system infections, 89-90, 93, 96, 101, 106, 115, 117-118, 122, 126, 130-131, 137, 141, 144, 150, 153. 155, 158, 160, 161, 163

genitourinary system infections, 233, 235

hemopoietic system infections, 203-204, 209, 213, 216, 220-221

laboratories for, 27

multiple systems infections, 239, 242-243, 246, 250, 255-256

respiratory system infections, 40, 46. 50, 53-54, 57-58, 61, 64, 67-68, 71, 72. 74, 77, 79, 81, 83

skin and joint infections, 164, 169-170, 173, 175, 181, 185, 187, 188-189, 191, 194, 195-197

see also Cell/tissue cultures:

Clinical signs;

Pathology;

Serologic tests;

Stain techniques

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

Diarrhea, 20,

digestive system infections, 102, 105. 111-118, 121, 129, 134, 140 , 149

hemopoietic system infections, 202, 262

skin and joint infections, 178

Differential diagnosis, skin infections, 195-197

Digestive system infections, 85-163

agents. 87, 91, 94-95, 98, 103-104, 11, 116-117, 119-120, 123-124, 127-128, 132-133, 139-140, 142, 146, 151, 156-157, 159. 160, 162

clinical signs, 88, 92, 95, 99-100, 105, 113, 117, 121, 125, 129, 134, 140, 143, 149, 152, 155, 157, 160, 161, 163

control, 75, 90, 93-94, 97, 101-102, 106, 115-116, 118, 122, 126, 131, 137-138, 141, 144-145, 150, 153, 156. 159. 161, 163

diagnosis, 89-90, 93, 96, 101, 106, 115, 117-118, 122, 126, 130-131, 137, 141, 144, 150, 153, 155, 158, 160, 161, 163

epizootiology, 88, 91-92, 95, 99, 104, 112-113, 117, 120-121, 124-125, 128-129, 133-134, 140, 142-143, 149, 152, 155, 157, 159, 161, 163

historic perspectives, 87, 91, 94, 97-98, 102-103, 111-112, 116, 118-119, 123-124, 127, 132, 139, 141-142

hosts, 87-88, 91, 95, 98-99, 104, 107-108, 112, 120, 124, 133, 142 , 149, 152, 155, 157, 159, 161, 162

parasites, 127. 145-163

pathology. 88-89, 92-93, 95-96, 100-101, 105-106, 113-114, 117, 121-122 , 125, 129-130, 134-137, 140-141, 143-144, 149-150, 152-153, 155, 158, 160, 161, 163

research interference, 90-91, 94, 97, 102, 109-111, 116, 118, 122-123, 126, 131, 138-139. 141, 145, 150-151, 153-154, 156, 158, 160, 161, 163

see also specific agents and organs

DNA viruses (agent characterization)

digestive system infections, 87, 91, 94-95, 123-124

multiple system infections, 237, 241, 244. 248

respiratory infections, 81

skin and joint infections, 166-167

see also specific agents

Dwarf tapeworm, 154-156

Dyspnea, 44. 52, 56. 66, 70, 212, 219, 262

E

Ear pathologies, 53, 63, 76, 143, 189. 195, 267-268

Ectromelia virus, 164, 165-171

Ectoparasites, 179-195

Empyema, 74, 268

Encephalitis, 102, 107, 224-225, 239, 268

Encephalitozoon cuniculi.222, 226-230

Encephalomyelitis, 102, 209, 222-225, 228, 250

Endometritis, 45, 268

Endoparasites, 144-163

Entamoeba muris, 12, 160-161

Enzyme-linked immunosorbent assay (ELISA), 22, 23

central nervous system infections, 229

digestive system infections, 88, 89-90, 93, 95, 96, 97, 101, 103, 108, 115, 122, 130

hemopoietic system infections, 203

multiple system infections, 242, 246, 250

respiratory infections, 40, 43, 46, 47, 50, 54, 57, 61, 81

skin and joint infections, 166, 169-170, 175

Eosinophilic crystals in lung, 39, 268

Eperythrozoon coccoides.198, 214-217

Epizootiology

central nervous system infections, 223-224, 227-228

definition of term, 32

digestive system infections, 88, 91-92, 95, 99, 104, 112-113, 117, 120-121, 124-125, 128-129, 133-134, 140, 142-143, 149, 152, 155, 157, 159, 161, 163

genitourinary system infections, 232-233, 234

hemopoietic system infections, 200-201, 207, 212, 215, 219

multiple systems infections, 237-238, 242, 245, 248-249, 254

prevalence data, general, 7-12

respiratory system infections, 37-38, 44, 49, 52, 55-56, 59-60, 62-63 , 66, 70, 73, 76, 78, 82, 248, 254

skin and joint infections, 167-168, 172, 177, 180, 186, 188, 191, 193

Escherichia coli, 126

Exanthema, 173. 268

Eye pathologies, 44, 49, 97, 100, 102, 189

see also Conjunctivitis;

Lacrymal glands

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

F

Facial abscesses, 183-184

G

Genitourinary system infections, 231-235

agents, 232, 234

clinical signs, 189, 233, 234

control, 233, 235

diagnosis, 233, 235

epizootiology, 44, 232-233, 234

hosts, 232, 234

pathology, 45. 233, 235

research history/prevalence, 231-232, 234

research interference, 234, 235

see also specific agents and organs

Germfree animal, defined, 6

see also Pathogen-free animal

Giardia muris, 12, 86, 151-154

Glomerulonephritis, 56, 202, 209, 268

Gnotobiotic animal and methods, defined, 6, 9

Growth retardation, 37, 102, 117, 262

H

Haemobartonella muris, 198, 211-214

Hair

digestive system infections, 149, 152, 157

respiratory infections, 66

skin conditions, noninfectious, 196, 197

Hantaviruses, 251-256

Harderian glands, 101

Head tilt, 44, 49, 263

Heart, 129, 268

Hemagglutination inhibition test (HAI), 45, 61, 83, 120, 122, 170, 173, 225, 241, 243, 246

Hemopoietic system infections, 198-221

agents, 199-200, 206, 212, 215, 218

clinical signs, 201-202, 207, 212, 215, 219

control, 204, 209-210, 213, 216, 221

diagnosis, 203-204, 209, 213, 216, 220-221

epizootiology, 200-201, 207, 212, 215, 219

hosts, 200, 206, 212, 215, 218

leukemia, 79, 171, 205, 217-221, 240, 243, 245, 246, 247

pathology, 202-203, 207-209, 212-213, 215-216, 219-220

research history/prevalence, 199. 205-206, 211, 214, 217

research interference, 204-205, 210-211, 213-214, 216-217, 221

see also specific agents and organs

Hemoglobinuria, 178, 212, 213. 263

Hemorrhages. 268

intestines, 130. 140

multiple system infections, 239, 254-255

skin and joint infections, 173. 193

Hepatic system, see Liver

Hepatitis virus, 20, 84, 86, 98. 102-111, 112

Herpesviruses, 87. 94

Historical perspectives/disease prevalence, 7-8, 9-10

central nervous system infections, 222-223, 226-227, 237, 241

definition of term, 32

digestive system infections, 87, 91, 94, 97-98, 102-103, 111-112, 116, 118-119, 123-124, 127. 132, 139, 141-142

genitourinary system infections, 231-232, 234

gnotobiotic methodology, 4, 9

hemopoietic system infections, 199, 205-206, 211, 214, 217

multiple systems infections, 236-237, 241, 243, 247, 252

respiratory system infections, 35-36, 42-43, 48, 51, 54-55, 59, 62 , 65, 69, 72, 73, 75, 77, 80, 81, 97-98, 187-188

skin and joint infections, 166, 171-172, 173-174, 177, 179-180, 182 , 185, 187-188, 190, 192

Hosts

central nervous system infections, 223, 227

definition of term, 32

digestive system infections, 87-88, 91, 95, 98-99, 104, 107-108, 112, 120, 124, 133. 142, 149, 152, 155, 157, 159, 161, 162

genitourinary system, 232, 234

hematopoietic system infections, 200, 206, 212, 215, 218

multiple systems infections, 237, 241. 245, 248, 253-254

respiratory system infections, 36-37, 44. 49, 52, 55, 59, 62, 66, 70, 72, 73, 75, 78, 82

skin and joint infections, 167, 172, 175, 177, 180, 183, 186, 188, 191, 193

see also Zoonotic agents;

Transplants, tissues and organs

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

Hunched posture, see Reluctance to move

Hymenolepis nana.154-156

Hyperexcitability. 224, 263

Hypersensitivity. cutaneous. 181, 184, 269

H-1 virus, 240-243, 246

I

Immune response, 275

athymic (nu/nu) mice, immune response, 260-261

central nervous system infections, 228, 229, 230

digestive system infections, 89, 96, 107-108, 109-110, 114, 125, 130, 135, 137, 143, 144, 151, 153, 154, 158

glomerulonephritis, 56, 202, 209

hemopoietic system infections, 198, 202, 203, 208-209, 210, 211, 212, 216-217

multiple system infections, 240, 243, 247, 249

respiratory infections, 35, 39, 41-42, 45-46, 50, 58, 64, 66, 67, 68, 69

skin and joint infections. 171, 176, 180, 185, 194

see also Serologic tests

Inapparent infections, see Subclinical infections

Inclusions, 269

intracytoplasmic, skin, 169, 191

intracytoplasmic and intranuclear, 250

intranuclear, 83, 88, 92, 96, 125

Indirect immunofluorescent antibody test (IFA), 22, 23

central nervous system infections, 229

digestive system infections, 88, 89, 95, 96, 101, 115, 117-118, 128 , 130

hemopoietic system infections, 200, 203, 216, 204, 221

multiple system infections, 242-243, 246

respiratory infections, 40, 50, 68, 71

skin and joint infections, 170

Infarcts, 53, 239, 269

Interference with research, see Research complications

Intestines, small, 269

blunting of villi, 107, 114, 117, 125

enteritis, 107, 117, 121, 125, 129, 130, 150, 152-153, 154-155

helminth parasite, 156

ileocecocolitis, 130, 136

protozoan parasites, 146, 149-151, 152-153

syncytial epithelial giant cells, 107, 117

J

Japan. 7-8, 10, 12

Jaundice. 105, 121, 238, 239, 263

Joints, see Skin and joint infections

K

Keratitis, 100

Keratoconus. 99, 181, 263

Kidneys

digestive system infections, 91, 92, 98, 121, 122, 126

genitourinary system infections, 228, 229, 233

multiple systems infections, 244, 248. 249. 250. 254

respiratory infections. 56, 74

Kilham rat virus, 10, 58, 236-240, 241. 242, 246

Klebsiella pneumoniae, 35, 72-75

K virus, 35, 81-84

Kyphosis, 178, 263

L

Lacrymal glands, 92, 93, 97, 99, 100, 102

Lactic dehydrogenase-elevating virus, 198, 205-211, 216

Laryngitis, 45, 49, 270

Leptospira interrogans serovar ballum.231-234

Leukemia. 79. 171, 205, 217-221, 240, 243, 245, 246, 247, 270

Life cycles, parasites

digestive system, 146, 152, 154-155, 157, 159, 160-161, 162

skin and joints, 180

Listeria monocytogenes.211

Litter size reduced, 37, 134, 263

Liver, 268, 270

central nervous system infections, 226

digestive system infections, 86, 98, 102-111, 112, 121, 129, 135, 136, 138

hemopoietic system infections, 202-203, 207, 216

hepatitis, 20, 53, 84, 86, 98, 102-111, 112, 268-269

jaundice, 105, 121, 238, 239, 263

multiple system infections, 238, 239, 243, 249

respiratory infections, 53, 56, 63, 74, 84

skin and joint infections, 169, 178

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

Lung pathology. 10, 35, 39, 45, 49, 52, 73, 83, 173, 249, 254, 255

Lymphadenopathy. 74, 76, 129, 178, 181, 219, 263, 270

Lymph nodes, 263, 271

digestive system infections, 95, 96, 100, 136

hemopoietic system infections, 207, 208, 219

respiratory infections, 63, 74, 76

skin and joint infections, 169, 178, 181, 189

Lymphocytic choriomeningitis virus, 10, 198, 199-205, 216

Lymphocytopenia, 208, 271

M

Malaria, 211, 214, 217

Mammary tumor virus, 192-195

Mastitis, 189, 263, 271

Mediastinitis, 53

Minute virus of mice, 243-247

Mites, 12, 179-182

Monitoring and monitored animals, 9, 13, 14, 15, 18, 21-27

digestive system infections, 97, 100

skin and joint infections, 179

Mouse adenovirus, 10, 123-126

Mouse cytomegalovirus, 87-91, 145

Mouse hepatitis virus, 84, 102-111

Mouse mammary tumor virus, 192-195

Mouse minute virus, 243-247

Mouse papule virus, 190-191

Mouse rotavirus, 20, 86, 111-116

Mouse thymic virus, 94-97

Mousepox virus, 164-171

Multiple systems infections, 236-256

agents, 237, 241, 244, 248, 252-253

clinical signs, 173, 238, 242, 245, 249, 254-255

control, 240, 243, 246, 251-252, 256

diagnosis, 239, 242-243, 246, 250, 255-256

epizootiology, 237-238, 242, 245, 248-249, 254

hosts, 237, 241, 245, 248, 253-254

pathology, 238-239, 242, 245-246, 249-250, 255

research history/prevalence, 236-237, 241, 243, 247, 252

research interference, 240, 243, 246-247, 252, 256

Murine respiratory mycoplasmosis (MRM), 44-45, 46. 47. 48, 49, 50

Mycobacterium avium-intracellulare.62-64

Mycoplasma arthritidis.11, 164. 173-176

Mycoplasma collis.35, 80-81

Mycoplasma muris.231, 234-235

Mycoplasma neurolyticum.35, 77-79

Mycoplasma pulmonis, 33-34, 36, 38, 40, 42-48, 50, 174, 188, 231

Myobia musculi, 179-182

Myocoptes musculinus.182

N

Necropsy

digestive system infections, 108, 117, 130, 158

respiratory infections, 53, 68, 74

Nematodes, 156-157, 159

Neoplasia, 271

leukemia, 79, 171, 205, 217-221, 240, 243, 245, 246, 247. 270

mammary glands, 192-195

salivary glands, 249

see also Carcinogenesis/spontaneous neoplasia

O

Otitis media, 143, 195, 189, 267

P

Pallor, see Anemia

Panophthalmitis, 189, 263

Papule virus, 190-191

Paralysis, 178, 207, 209, 224, 249, 250, 263-264

Parasitic infections, 45

blood. 214, 216, 217

digestive system, 127, 145-163

ectoparasites, 179-195

endoparasites. 144-163

genitourinary system, 226-230

multiple systems, 250

prevalence data, 12

skin and joints, 179-185

testing for, 24

see also Life cycles, parasites;

Protozoa

Pasteurella pneumotropica.11, 35, 187-190

Pathogen-free animal, 6, 9, 13-16

see also Specific pathogen-free animal

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

Pathology, 266-274

central nervous system infections, 224-225, 228-229

definition of term, 32

digestive system infections, 88-89, 92-93, 95-96, 100-101, 105-106, 113-114, 117, 121-122, 125, 129-130, 134-137, 140-141, 143-144, 149-150 , 152-153, 155, 158, 160, 161, 163

genitourinary system infections, 233, 235

hemopoietic system infections, 202-203. 207-209, 212-213, 215-216, 219-220

multiple systems infections, 238-239, 242, 245-246, 249-250, 255

respiratory system infections, 38-40, 44-45, 49-50, 52-53, 56-57, 60-61, 63, 66-68, 71, 72, 74, 76, 78-79, 81, 82-83, 105, 106, 107, 121, 173, 255

skin and joint infections, 168-169, 173, 175, 178, 180-181, 184-185, 186, 188, 191, 193-194

see also Clinical signs;

specific organs and systems

Peritonitis, 53, 57, 136, 271

Pharmacokinetics, 131, 275

Photophobia, 99, 178, 264

Pinworm, 20, 156-160

Pleural effusion, 39, 173, 271

Pleuritis, 53, 57, 271

Pneumocystis carinii, 35, 64-69

Pneumonia, 10, 76, 173, 271-272

broncho, 45, 49, 53

embolic, 56

interstitial, 38, 60, 71, 83. 100, 106-107

Pneumonia virus of mice. 35, 50, 59-62, 82

Pododermatitis, 184, 264, 272

Polioencephalomyelitis, see Encephalomyelitis

Polyoma virus. 19, 81, 205, 247-251

Polyplax serrata, 215

Polypnea. 44, 264

Poxviruses, 164-171, 171-173, 178

Preputial gland abscesses, 184

Priapism, 178, 180, 264

Protozoa

central nervous system infections, 227

digestive system infections, 146, 149-153, 160, 162

respiratory infections, 65

serologic tests, 22

Pruritis, 178, 180, 183, 264

Pseudomonas aeruginosa, 11, 141-145

Pseudotuberculosis, 57

R

Radfordia affinis.182

Radioimmunoassays. 54, 115

Rat coronavirus, 58

Rat cytomegalovirus, 91-94

Rat rotavirus, 116-118

Rectal prolapse, 139, 140, 157, 264

Reluctance to move, 44, 49, 70, 129, 134, 149, 201, 264

Reovirus-3, 10, 19. 118-123

Research, see Historical perspectives/disease prevalence

Research complications, 3, 275-276

central nervous system infections, 226, 229-230

definition of term, 32

digestive system infections. 90-91, 94, 97, 102, 109-111, 116, 118 , 122-123, 126, 131, 138-139, 141, 145, 150-151, 153-154, 156, 158 , 160, 161, 163

genitourinary system infections, 234, 235

hemopoietic system infections, 204-205, 210-211, 213-214, 216-217, 221

multiple systems infections, 240, 243, 246-247, 252, 256

respiratory system infections, 41-42, 47-48, 50. 54, 58, 61-62, 64 , 69, 72, 75, 77, 79, 81, 84, 102, 123

significance, general definition, 31

skin and joint infections, 171, 173, 176, 179, 181-182, 185, 187. 190, 191, 194-195

Respiratory system infections, 33-84, 231

agents, 34, 36, 43-44, 48-49, 51-52, 54-55, 59, 62, 65-66, 70, 72, 73, 75, 77-78, 80, 81-82

airflow barrier systems. 19-20

clinical signs, 37-38, 44, 49, 52, 56, 60, 63, 66, 70, 72, 74, 76, 78, 80, 82, 172, 189

control techniques, 40-41. 46-47, 50, 54, 58, 61, 64, 69, 71, 72, 75, 77, 79, 81, 83

diagnosis. 40, 46, 50, 53-54, 57-58, 61, 64, 67-68, 71, 72, 74, 77 , 79, 81, 83

epizootiology. 37-38, 44, 49, 52, 55-56, 59-60, 62-63, 66, 70, 73, 76, 78, 82, 248, 254

hosts, 36-37, 44, 49, 52, 55, 59, 62, 66, 70, 72, 73, 75, 78, 82

pathology, 38-40, 44-45, 49-50, 52-53, 56-57, 60-61, 63, 66-68, 71 , 72, 74, 76, 78-79, 81, 82-83, 105, 106, 107, 121, 173, 255

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

research history/prevalence, 33, 35-36, 42-43, 48, 51, 54-55, 59, 62, 65, 69, 72, 73, 75, 77. 80, 81, 97-98, 103, 187-188

research interference, 41-42, 47-48, 50, 54, 58, 61-62, 64, 69, 72 , 75, 77, 79, 81, 84, 102, 123

see also specific agents and organs

Rhinitis, 45, 53, 76, 272

Ringtail. 164, 197

RNA viruses (agent characterization)

central nervous system infections, 223

digestive system infections, 86, 98, 103-104, 112, 116, 119-120

hemopoietic system infections, 199-200, 206, 218

multiple systems infections. 252-253

respiratory infections, 36, 59, 84, 98

skin and joint infections, 192

see also specific agents

Rolling, see Circling and rolling

Rotavirus, 20, 86, 111-118

Runting, see Wasting syndrome

S

Salivary glands and saliva, 87, 88, 91-92, 95, 96, 99, 100, 101, 102, 249, 272

Salmonella enteritidis,11, 86, 132-139, 169, 178

Salpingitis, 45

Sampling, 25-26

Scrotal cyanosis, 238

Scrotal hemorrhage, 239

SDA/RCV, 10

Self-mutilation, 184, 185, 195

Sendai virus, 10, 34, 35-41, 50, 58

Sentinel animals, 27

Septicemia, 272

digestive system infections, 136, 143, 144, 145

genitourinary system infections, 233

respiratory infections, 54, 56-57

skin and joint infections, 178, 203

Serologic tests, 22-24

central nervous system infections, 225-226, 227, 229

digestive system infections. 101, 103, 117-118, 124, 128, 133

genitourinary system infections, 232, 233

multiple system infections, 237, 239-243, 246, 255

respiratory infections, 43, 54, 61, 68, 74, 75

skin and joint infections. 169, 175

see also Enzyme-linked immunosorbent assay;

Hemagglutination inhibition test;

Indirect immunofluorescent antibody test

Sialodacryoadenitis virus, 35, 43, 45, 58, 97-102, 189

Silver stain, see Stain techniques

Skin and joint infections. 164-197

agents, 166-167, 172, 174-175, 177, 182-183, 186, 188, 190, 192

clinical signs. 168, 172-173, 175, 178, 180, 183-184, 186, 188, 193

control, 170-171, 173, 176, 178-179, 181, 185, 187, 190, 191, 194

diagnosis, 164, 169-170, 173, 175, 181, 185, 187, 188-189, 191, 194

epizootiology, 167-168, 172, 177, 180, 186, 188, 191, 193

hosts, 167, 172, 175, 177, 180, 183, 186, 188, 191, 193

pathology, 168-169, 173, 175, 178, 180-181, 184-185, 186, 188, 191 , 193-194

parasites, 179-182

research history/prevalence. 166, 171-172, 173-174, 177, 179-180, 182, 185, 187-188, 190, 192

research interference, 171. 173, 176, 179, 181-182, 185, 187, 190, 191, 194-195

see also Dermatitis and alopecia;

specific agents

Skin conditions, noninfectious, 195-197

Skin ulceration, 180, 183, 186, 264

Sneezing, 44, 74, 99, 264

Snuffling, 44, 52, 264

Social behavior, see Behavioral trauma

Specific pathogen-free animal, 6, 9

central nervous system infections, 226

digestive system infections, 153

hemopoietic system infections, 204, 216

multiple system infections, 240, 246, 255

skin and joint infections. 176

Spinal cord, 239, 250, 272

Spironucleus muris, 12, 86, 146, 149-151

Spleen, 239, 272-273

central nervous system infections, 226, 230

digestive system infections, 92, 95, 96, 106, 135, 136, 151

hemopoietic system infections, 207, 213, 214, 215-216

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

respiratory system infections, 41, 51, 63

skin and joint infections, 169, 171, 178

Stain techniques

digestive system infections, 130, 150, 161, 163

hemopoietic system infections, 213, 216, 218

respiratory infections, 50, 68

Standards, 13-14, 21

Staphylococcus aureus.123, 164-165, 182-185

Streptobacillus moniliformis, 164, 169, 176-179

Streptococcus pneumoniae, 34, 51-54

Streptococcus pyogenes, 35, 75-77

Subclinical infections, 263, 276

central nervous system infections, 224

digestive system, 87, 88, 92, 95, 97, 99-100, 105, 111, 128, 129, 131, 132, 134, 149, 151, 152, 157, 160, 161

genitourinary system infections, 233

hemopoietic system infections. 201, 207, 210, 212, 214

multiple system infections, 238, 240, 242, 245

respiratory, 33, 37, 44, 46, 47, 54, 55, 57, 60, 66, 69, 70, 72, 78, 80, 82, 174

skin and joints, 11, 168, 172, 174, 175, 176, 178, 180

Surveillance, see Monitoring and monitored animals

Swelling (endema), 99, 169, 178, 197, 264

Symptoms, see Clinical signs;

specific symptoms

Syphacia obvelatalmuris, 20, 156-158

Synctal giant cells. 38, 45, 107, 117, 273

T

Terminology

agent characterization, 31-32

barrier techniques, 6, 17-18

infection vs disease, 3-4

microbial and pathogen terms, 4-9, 13

Teratogenic effects, 239, 273

Testes, 53, 239, 273

Theiler's virus, 10-11, 222-226

Thrombosis, 239, 273

Thymus, 94-97, 100, 207, 208, 220, 273

Tissue cultures, see Cell/tissue cultures

Toolan H-1 virus, 10

Tracheitis, 39, 45, 49, 273

Transplants, tissue and organs, 276

central nervous system infections, 228, 230

digestive system infections, 86, 90, 94, 104, 107, 121, 122-123, 131, 138

hemopoietic system infections, 198, 199, 200, 203-211, 213, 214

multiple system infections, 238, 240, 243, 245, 246, 249, 250, 251 , 255-256

respiratory infections, 41, 42, 84, 84

skin and joint infections, 176

Transportation of animals, general, 13-14

Tremors, 224, 264

Tritrichomonas muris.12, 162-163

Tumors, 276

central nervous system infections, 228, 230

digestive system infections, 86, 90, 94, 104, 107, 121, 122-123, 131, 138

hemopoietic system infections, 198, 199, 200, 203-211, 213, 214

multiple system infections, 238, 240, 243, 245, 246, 249, 250, 251 , 255-256

respiratory infections, 41, 42, 48, 84

skin and joint infections, 176, 192-195, 199

see also Neoplasia

Tyzzer's disease, 127-131

U

United Kingdom, 7-8, 9, 10

Uterine pathologies, 45, 239, 274

V

Vaccination

digestive system infections, 116, 144-145

respiratory infections, 41, 54

skin and joint infections, 170-171

Viral agents

prevalence, general, 7-8, 9-10

respiratory, 54

skin and joint infections, 190

tests for, 22-24

see also DNA viruses (agent characterization);

Poxviruses;

RNA viruses (agent characterization);

specific agents

W

Wasting syndrome, 105, 238, 246, 249, 265

see also Anorexia:

Weight loss

Weaning behavior, 195-196

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×

Weight loss

birth weight reduced, 38, 134, 261

digestive system infections, 102, 105, 116, 134, 140, 149, 151, 152 , 155

emaciation, 262

hemopoietic system, 201, 212

multiple systems, 238, 250

respiratory infections, 44, 52, 56, 66, 67, 70

skin and joint infections, 178

West Germany, 12

Whisker-trimming, 196

Wounds, 195-196

X

X-irradiation, 92, 131, 152, 154, 171, 205, 209, 214

Z

Zoonotic agents. 276

central nervous system infections, 229

digestive system infections, 116, 118, 133, 138, 154, 156

genitourinary infections, 230, 232, 233, 234

hemopoietic system infections. 199, 200, 201-202, 204, 205

multiple system infections, 251-256

respiratory infections. 52

skin and joint infections, 172, 177, 178, 179, 185-187

Suggested Citation:"Index." National Research Council. 1991. Infectious Diseases of Mice and Rats. Washington, DC: The National Academies Press. doi: 10.17226/1429.
×
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This new edition—a must for all researchers who use these lab animals—provides practical suggestions for breeding, keeping, and identifying pathogen-free laboratory rodents. It contains three informative sections. The first, Principles of Rodent Disease Prevention, summarizes methods for eliminating infectious agents. It offers information on pathogen terminology; pathogen status of rodents; and breeding, transporting, isolating, testing, and diagnosing rodents. The second section, Individual Disease Agents and Their Effects on Research, describes the diagnosis and control of each infectious agent, and the last section, Diagnostic Indexes: Clinical Signs, Pathology, and Research Complications, contains informative tables covering all the diseases listed in the volume, arranged to help in the diagnosis of infected animals.

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