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Suggested Citation:"Attachment 1: Statement of Task." National Academies of Sciences, Engineering, and Medicine. 2018. Review of Report and Approach to Evaluating Long-Term Health Effects in Army Test Subjects: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/25025.
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Attachment 1

Statement of Task

An ad hoc committee will evaluate the report Assessment of Potential Long-Term Health Effects on Army Human Test Subjects of Relevant Biological and Chemical Agents, Drugs, Medications and Substances: Literature Review and Analysis. The committee will determine whether the report appropriately identifies potential long-term health effects from exposure during testing and uses an adequate weight-of-evidence approach to characterize the strength of association between agents and their potential effects. The general approach developed by the Army to evaluate agent- and outcome-specific associations will also be reviewed. The committee will prepare two reports: an interim letter report that documents the committee’s overarching findings and their supporting evidence, followed by a final report at the end of the project that provides additional technical details.

Sponsor: U.S. Army

Suggested Citation:"Attachment 1: Statement of Task." National Academies of Sciences, Engineering, and Medicine. 2018. Review of Report and Approach to Evaluating Long-Term Health Effects in Army Test Subjects: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/25025.
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Review of Report and Approach to Evaluating Long-Term Health Effects in Army Test Subjects: Interim Report Get This Book
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Between 1942 and 1975, the U.S. Army conducted tests with human subjects to study the effects of a variety of agents, including chemical warfare and biological agents. The potential long-term health effects on the test subjects from their exposures have been evaluated periodically, most recently in a report titled Assessment of Potential Long-Term Health Effects on Army Human Test Subjects of Relevant Biological and Chemical Agents, Drugs, Medications and Substances: Literature Review and Analysis (the Report), which was prepared by a contractor to assist the Army with making determinations about providing medical care to former test subjects. In response to a request by the Army, the National Academies of Sciences, Engineering, and Medicine formed a committee that was tasked with examining whether the Report appropriately identified potential long-term health effects from exposure to the test agents and whether an adequate weight-of-evidence approach was used to characterize the strength of the associations between the agents and their potential health effects. The committee was made aware at its first meeting on November 30, 2017, that the Army had already begun to receive applications for medical care and that some determinations may need to be made before the committee’s evaluation of the Report was completed. Because of this urgency, the Army developed a process by which applications for medical care will be reviewed, and as a result, the committee was given the additional task of reviewing the Army’s Memorandum that describes the approach that will be used by the Army to evaluate agent- and outcome-specific associations. This interim report was prepared to facilitate the Army’s deliberations. A review of the Report is presented first, followed by a review of the Memorandum.

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