FIGURE D-1 Relationships between sodium intake, surrogate marker (blood pressure) and health outcomes. Surrogate markers are a laboratory measurement or physical sign used as an indicator of a health outcome. Health outcomes represent incidence (e.g., development) of a disease or mortality.
SOURCE: Adapted from Russell et al., 2009. Reprinted with permission from American Journal of Clinical Nutrition (2009; 89:728-733).
Russell, R., M. Chung, E. M. Balk, S. Atkinson, E. L. Giovannucci, S. Ip, A. H. Lichtenstein, S. T. Mayne, G. Raman, A. Catharine Ross, T. A. Trikalinos, K. P. West, Jr., and J. Lau. 2009. Opportunities and challenges in conducting systematic reviews to support the development of nutrient reference values: Vitamin A as an example. American Journal of Clinical Nutrition 89(3):728-733.