A
Workshop Agenda
Applying an Implementation Science Approach to
Genomic Medicine: A Workshop
November 19, 2015
National Academy of Sciences Building
Lecture Room
2101 Constitution Avenue, NW
Washington, DC
MEETING OBJECTIVES
- To elucidate options for accelerating the pace of implementation and evidence generation in genomic medicine by convening medical implementation science experts with stakeholders representing the continuum of genomics translational research.
- To discuss possible strategies for reaching and engaging diverse populations when introducing genomic medicine into practice.
- To explore the challenges, successes, and best practices that facilitate rapid and appropriate translation of genomic knowledge from early discovery to population health.
AGENDA
8:30–8:35 a.m. | Welcoming Remarks |
Sharon F. Terry, Roundtable Co-Chair | |
President and Chief Executive Officer Genetic Alliance |
|
Geoffrey Ginsburg, Roundtable Co-Chair | |
Director, Duke Center for Applied Genomics & Precision Medicine; Professor of Medicine and of Pathology and Biomedical Engineering, Duke University Medical Center |
INTRODUCTION: OPPORTUNITIES IN GENOMICS THAT CHALLENGE THE TRADITIONAL IMPLEMENTATION PATHWAY
Objectives: | To define and explore the stages and roles of implementation science from basic science discoveries to advancing genomic medicine in routine clinical care |
8:35 a.m. | Charge to Workshop Speakers and Participants: Considering the Role of Implementation Science Across the Translational Spectrum in Genomics |
Greg Feero, Workshop Co-Chair | |
Associate Editor, Journal of the American Medical Association; Faculty, Maine Dartmouth Family Medicine Residency Program | |
Debra Leonard, Workshop Co-Chair | |
Professor and Chair of Pathology and Laboratory Medicine | |
University of Vermont Medical Center | |
8:45 a.m. | Overview of Implementation Science: Methods and Approaches |
David Chambers | |
Deputy Director for Implementation Science National Cancer Institute | |
Brian Mittman | |
Research Scientist III, Research & Evaluation | |
Kaiser Permanente Research | |
Senior Advisor, Veterans Affairs Center for Implementation Practice and Research Support, Los Angeles, CA | |
Consultant, University of California, Los Angeles, Institute for Innovation in Health | |
Senior Advisor, RAND Health | |
9:30 a.m. | Clarifying Questions |
SESSION I: DESIGNING FOR IMPLEMENTATION: ENGAGING LARGE POPULATIONS FOR ANALYSIS
Objectives: | To assess best practices for engaging diverse patient and provider groups and evaluating how information collected from large groups could be leveraged for discovery efforts and improved health outcomes |
Moderator: | Bruce Blumberg, Institutional Director of Graduate Medical Education, Northern California Kaiser Permanente |
9:40 a.m. | Andrew Faucett |
Director of Policy and Education | |
Geisinger Health System | |
Consuelo H. Wilkins | |
Executive Director, Meharry-Vanderbilt Alliance | |
Associate Professor of Medicine | |
Vanderbilt-Ingram Cancer Center | |
Marc LePage | |
President and Chief Executive Officer | |
Génome Québec | |
10:30 a.m. | Break |
10:45 a.m. | Discussion with Speakers, Reactants, and Attendees |
Speakers | |
Andrew Faucett | |
Consuelo H. Wilkins | |
Marc LePage | |
Reactants | |
Bernice Coleman | |
Nurse Scientist and Nurse Practitioner | |
Heart Transplantation and Mechanical Assist Device Programs, Cedars Sinai Medical Center, Los Angeles | |
Robert McDonough | |
Head of Clinical Policy Research & Development | |
Aetna | |
Brian Mittman | |
Research Scientist III, Research & Evaluation | |
Kaiser Permanente Research | |
Senior Advisor, Veterans Affairs Center for Implementation Practice and Research Support, Los Angeles, CA | |
Consultant, University of California, Los Angeles, Institute for Innovation in Health | |
Senior Advisor, RAND Health | |
Jane Perlmutter | |
President and Founder | |
Gemini Group | |
Alexandra Shields | |
Associate Professor, Harvard Medical School and Massachusetts General Hospital (MGH) | |
Director, Harvard/MGH Center on Genomics, Vulnerable Populations, and Health Disparities |
SESSION II: EXPLORING MODELS FOR IMPROVING IMPLEMENTATION WHILE GENERATING EVIDENCE IN CLINICAL SETTINGS
Objective: | To explore case studies where implementation in clinical care has had varying degrees of success in achieving practice change |
Moderator: | Catherine Wicklund, Past President, |
National Society of Genetic Counselors | |
Director, Graduate Program in Genetic Counseling, Northwestern University | |
11:30 a.m. | Approaches to Implementation |
Edward Kim | |
Chair, Solid Tumor Oncology and Investigational Therapeutics and the Donald S. Kim Distinguished Chair for Cancer Research | |
Levine Cancer Institute, Carolinas HealthCare System | |
Mary Norton | |
Professor of Obstetrics, Gynecology, and Reproductive Sciences | |
University of California, San Francisco | |
Stephen Kimmel | |
Professor of Medicine | |
University of Pennsylvania School of Medicine | |
12:20 p.m. | Discussion with Speakers, Reactants, and Attendees |
Speakers | |
Edward Kim | |
Mary Norton | |
Stephen Kimmel | |
Reactants | |
Bernice Coleman | |
Robert McDonough | |
Brian Mittman |
Jane Perlmutter | |
Alexandra Shields | |
1:00 p.m. | WORKING LUNCH |
SESSION III: POPULATION HEALTH AND GENOMICS: INCREMENTAL IMPLEMENTATION OR RADICAL REFORM?
Objectives: | To explore effective strategies and infrastructure that facilitates implementation and how these could be applied to advance the future of genomic medicine |
Moderator: | Greg Feero, Workshop Co-Chair; |
Associate Editor, Journal of the American Medical Association; and Faculty, Maine Dartmouth Family Medicine Residency Program | |
2:00 p.m. | Deb Duquette |
Genomics Coordinator | |
Michigan Department of Health and Human Services | |
Marc LePage | |
President and Chief Executive Officer | |
Génome Québec | |
Toni Pollin | |
Associate Professor, Medicine | |
University of Maryland School of Medicine | |
2:50 p.m. | Discussion with Speakers, Reactants, and Attendees |
Speakers | |
Deb Duquette | |
Marc LePage | |
Toni Pollin | |
Reactants | |
Bernice Coleman | |
Robert McDonough |
Brian Mittman | |
Jane Perlmutter | |
Alexandra Shields | |
3:30 p.m. | Break |
SESSION IV: ACHIEVING THE VISION
Objectives: | To reflect on the potential value of implementation science to the translation of genomics to achieve improved health outcomes. To provide concrete examples of how integration of principles of implementation science might accelerate the translational pipeline now and over the next 5–10 years. |
Moderator: | Debra Leonard, Workshop Co-Chair; Professor and Chair of Pathology and Laboratory Medicine, University of Vermont Medical Center |
3:45 p.m. | Stakeholder Reaction Panelists |
Health Care Provider Perspective | |
Bernice Coleman | |
Payer Perspective | |
Bob McDonough | |
Patient Perspective | |
Jane Perlmutter | |
Health Disparities Perspective | |
Alexandra Shields | |
4:20 p.m. | Discussion with Reactants and Attendees |
5:00 p.m. | Concluding Remarks |
Summary of Important Points and Potential Approaches to Genomic Medicine Implementation | |
David Chambers | |
Deputy Director for Implementation Science | |
National Cancer Institute | |
5:20 p.m. | Adjourn |
Greg Feero, Workshop Co-Chair | |
Associate Editor, Journal of the American Medical Association; Faculty, Maine Dartmouth Family Medicine Residency Program | |
Debra Leonard, Workshop Co-Chair | |
Professor and Chair of Pathology and Laboratory Medicine | |
University of Vermont Medical Center |