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Suggested Citation:"Appendix A: Public Meeting Agendas." National Academies of Sciences, Engineering, and Medicine. 2020. Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis. Washington, DC: The National Academies Press. doi: 10.17226/25688.
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Page 379
Suggested Citation:"Appendix A: Public Meeting Agendas." National Academies of Sciences, Engineering, and Medicine. 2020. Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis. Washington, DC: The National Academies Press. doi: 10.17226/25688.
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Page 380
Suggested Citation:"Appendix A: Public Meeting Agendas." National Academies of Sciences, Engineering, and Medicine. 2020. Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis. Washington, DC: The National Academies Press. doi: 10.17226/25688.
×
Page 381
Suggested Citation:"Appendix A: Public Meeting Agendas." National Academies of Sciences, Engineering, and Medicine. 2020. Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis. Washington, DC: The National Academies Press. doi: 10.17226/25688.
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Page 382

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Appendix A Public Meeting Agendas FIRST PUBLIC MEETING January 28, 2019 National Academy of Sciences Building 2101 Constitution Avenue, NW Washington, DC 20001 Board Room 1:00–1:10 p.m. ET Welcome and introductions; Conduct of the Open Session Savitz, Ph.D., Committee Chair David 1:10–1:50 p.m. Charge to the Committee  Peter R. Rumm, M.D., M.P.H., Director, Pre-9/11 Era Environmental Health Program, Department of Veterans Affairs, with Dr. R. Loren Erickson, Chief Consultant, Post Deployment Health 1:50–2:20 p.m. Overview of Antimalarials Use Policy and Monitoring in Service Members  COL Andrew Wiesen, M.D., M.P.H., Director, Preventive Medicine, Health Readiness Policy and Oversight, Office of the Assistant Secretary of Defense (Health Affairs) 379

380 LONG-TERM HEALTH EFFECTS OF ANTIMALARIAL DRUGS 2:20–2:50 p.m.  Drug Administration Adverse Events Report- Food and ing System  Kelly Yoojung Cao, Pharm.D., Team Leader, Division of Pharmacovigilance II, Food and Drug Administration 2:50–3:30 p.m. Centers for Disease Control and Prevention Monitoring of Malaria and Research Related to Antimalarials Use  Kathrine Tan, M.D., M.P.H., Chief, Domestic Response Unit, Malaria Branch, Centers for Disease Control and Prevention 3:30–3:50 p.m. Identifying and Evaluating Sources of Evidence of Quinism: A Novel Disease Affecting U.S. Veterans   M.P.H., Dr.P.H., Executive Remington Nevin, M.D., Director, The Quinism Foundation 3:50–4:20 p.m.1 Public Comments Limited to 3 minutes per individual/organization 4:20 p.m. OPEN SESSION ENDS 1  To be extended if needed to accommodate those wishing to make a public statement.

APPENDIX A 381 SECOND PUBLIC MEETING AGENDA March 27, 2019 OPEN SESSION Keck Building 500 Fifth Street, NW, Washington, DC Keck Room 105 9:30–9:35 a.m. ET  elcome and Introductions; Conduct of the Open Ses- W sion David Savitz, Ph.D., Committee Chair 9:35–10:05 a.m.  Overview of Antimalarials Use Policy and Monitoring in Peace Corps Volunteers  Kyle Petersen, D.O, F.I.D.S.A., F.A.C.P., Director of Epidemiology, Peace Corps 10:05–10:25 a.m. Antimalarials—Use Policy and Monitoring in Deployed Employees of Department of State Kim Ottwell, M.D., Clinical Director of Clinical Services 10:25–11:25 a.m. Neurotoxic Mechanisms of Antimalarials  Thomas Brewer, M.D., University of Washington, and Principle, Global Enterics, LLC 11:25–11:50 a.m. Public Comments Limited to 3 minutes per individual/organization 11:50 a.m. OPEN SESSION ENDS

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Among the many who serve in the United States Armed Forces and who are deployed to distant locations around the world, myriad health threats are encountered. In addition to those associated with the disruption of their home life and potential for combat, they may face distinctive disease threats that are specific to the locations to which they are deployed. U.S. forces have been deployed many times over the years to areas in which malaria is endemic, including in parts of Afghanistan and Iraq. Department of Defense (DoD) policy requires that antimalarial drugs be issued and regimens adhered to for deployments to malaria-endemic areas. Policies directing which should be used as first and as second-line agents have evolved over time based on new data regarding adverse events or precautions for specific underlying health conditions, areas of deployment, and other operational factors

At the request of the Veterans Administration, Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis assesses the scientific evidence regarding the potential for long-term health effects resulting from the use of antimalarial drugs that were approved by FDA or used by U.S. service members for malaria prophylaxis, with a focus on mefloquine, tafenoquine, and other antimalarial drugs that have been used by DoD in the past 25 years. This report offers conclusions based on available evidence regarding associations of persistent or latent adverse events.

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