National Academies Press: OpenBook

Ovarian Cancers: Evolving Paradigms in Research and Care (2016)

Chapter: Appendix A: Acronyms and Abbreviations

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Suggested Citation:"Appendix A: Acronyms and Abbreviations." National Academies of Sciences, Engineering, and Medicine. 2016. Ovarian Cancers: Evolving Paradigms in Research and Care. Washington, DC: The National Academies Press. doi: 10.17226/21841.
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Appendix A

Acronyms and Abbreviations

ABOG American Board of Obstetrics and Gynecology
ABOUT American BRCA Outcomes and Utilization of Testing [Patient-Powered Research Network]
ACA Patient Protection and Affordable Care Act
ACMG American College of Medical Genetics and Genomics
ACOG American Congress of Obstetricians and Gynecologists
ACS American College of Surgeons
ACT adoptive cell therapy
AHRQ Agency for Healthcare Research and Quality
ASCO American Society of Clinical Oncology
 
BER base excision repair
BMI body mass index
BOT borderline ovarian tumor
BRCA breast cancer genes 1 and 2
BSO bilateral salpingo-oophorectomy
BSOR bilateral salpingectomy with ovarian retention
 
CA-125 cancer antigen 125
CAM complementary and alternative medicine
CCC clear cell carcinoma
CDC Centers for Disease Control and Prevention
CMS Centers for Medicare & Medicaid Services
CPTAC Clinical Proteomic Tumor Analysis Consortium
CT computed tomography
Suggested Citation:"Appendix A: Acronyms and Abbreviations." National Academies of Sciences, Engineering, and Medicine. 2016. Ovarian Cancers: Evolving Paradigms in Research and Care. Washington, DC: The National Academies Press. doi: 10.17226/21841.
×
CTCAE Common Terminology Criteria for Adverse Events
CTEP Cancer Therapy Evaluation Program
 
D&I dissemination and implementation
DNA deoxyribonucleic acid
DoD U.S. Department of Defense
 
EBI evidence-based intervention
EC endometrioid carcinoma
EGFR epidermal growth factor receptor
EMT epithelial to mesenchymal transition
 
FDA U.S. Food and Drug Administration
FIGO International Federation of Gynecology and Obstetrics
FORCE Facing Our Risk of Cancer Empowered
FTE fallopian tube epithelium
 
GEMM genetically engineered mouse model
GH growth hormone
GOG Gynecologic Oncology Group
 
HBOC hereditary breast and ovarian cancer [syndrome]
HE-4 human epididymis protein 4
HGSC high-grade serous carcinoma
HHS U.S. Department of Health and Human Services
HPV human papillomavirus
HR homologous recombination
 
IGF-1 insulin-like growth factor 1
IOM Institute of Medicine
IP intraperitoneal
IrRC immune-related response criteria
IV intravenous
 
LBA laboratory biomarker analysis
LGSC low-grade serous carcinoma
 
MAPK mitogen-activated protein kinase
MC mucinous carcinoma
miR microRNA
MMS multimodal screening
MRI magnetic resonance imaging
 
Suggested Citation:"Appendix A: Acronyms and Abbreviations." National Academies of Sciences, Engineering, and Medicine. 2016. Ovarian Cancers: Evolving Paradigms in Research and Care. Washington, DC: The National Academies Press. doi: 10.17226/21841.
×
NACT neoadjuvant chemotherapy
NCCN National Comprehensive Cancer Network
NCI National Cancer Institute
NGS next-generation sequencing
NHEJ nonhomologous end joining
NIH National Institutes of Health
NOCC National Ovarian Cancer Coalition
NRC National Research Council
NSGC National Society of Genetic Counselors
 
OC oral contraceptive
OCNA Ovarian Cancer National Alliance
OCRF Ovarian Cancer Research Fund
OCRP Ovarian Cancer Research Program
OCS Office of Cancer Survivorship
OSE ovarian surface epithelium
 
PARP poly ADP ribose polymerase
PCORI Patient-Centered Outcomes Research Institute
PCOS polycystic ovarian syndrome
PDS primary debulking surgery
PDX patient-derived xenograft
PFS progression-free survival
PID pelvic inflammatory disease
PLCO prostate, lung, colorectal, and ovarian [cancer screening trial]
PPC primary palliative care
PRO patient-reported outcome
 
QOL quality of life
 
RCT randomized controlled trial
RMI Risk of Malignancy Index
RNA ribonucleic acid
ROCA risk of ovarian cancer algorithm
ROMA risk of ovarian malignancy algorithm
RRSO risk-reducing salpingo-oophorectomy
 
SBT serous borderline tumor
SEER surveillance, epidemiology, and end results
SGO Society of Gynecologic Oncology
SNP single-nucleotide polymorphism
SPC specialty palliative care
Suggested Citation:"Appendix A: Acronyms and Abbreviations." National Academies of Sciences, Engineering, and Medicine. 2016. Ovarian Cancers: Evolving Paradigms in Research and Care. Washington, DC: The National Academies Press. doi: 10.17226/21841.
×
SPORE Specialized Program of Research Excellence
STIC serous tubal intraepithelial carcinoma
 
TCGA The Cancer Genome Atlas
TVU transvaginal ultrasound
 
UKCTOCS United Kingdom Collaborative Trial of Ovarian Cancer Screening
USPSTF U.S. Preventive Services Task Force
 
VEGF vascular endothelial growth factor
VEGFR vascular endothelial growth factor receptor
 
WOO window of opportunity
Suggested Citation:"Appendix A: Acronyms and Abbreviations." National Academies of Sciences, Engineering, and Medicine. 2016. Ovarian Cancers: Evolving Paradigms in Research and Care. Washington, DC: The National Academies Press. doi: 10.17226/21841.
×
Page 299
Suggested Citation:"Appendix A: Acronyms and Abbreviations." National Academies of Sciences, Engineering, and Medicine. 2016. Ovarian Cancers: Evolving Paradigms in Research and Care. Washington, DC: The National Academies Press. doi: 10.17226/21841.
×
Page 300
Suggested Citation:"Appendix A: Acronyms and Abbreviations." National Academies of Sciences, Engineering, and Medicine. 2016. Ovarian Cancers: Evolving Paradigms in Research and Care. Washington, DC: The National Academies Press. doi: 10.17226/21841.
×
Page 301
Suggested Citation:"Appendix A: Acronyms and Abbreviations." National Academies of Sciences, Engineering, and Medicine. 2016. Ovarian Cancers: Evolving Paradigms in Research and Care. Washington, DC: The National Academies Press. doi: 10.17226/21841.
×
Page 302
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In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease--several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades is likely due to several factors, including the lack of research being performed by specific disease subtype, lack of definitive knowledge of the cell of origin and disease progression, and incomplete understanding of genetic and non-genetic risk factors.

Ovarian Cancers examines the state of the science in ovarian cancer research, identifies key gaps in the evidence base and the challenges to addressing those gaps, considers opportunities for advancing ovarian cancer research, and examines avenues for translation and dissemination of new findings and communication of new information to patients and others. This study makes recommendations for public- and private-sector efforts that could facilitate progress in reducing the incidence of morbidity and mortality from ovarian cancers.

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