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Issues in Risk Assessment (1993)

Chapter: 9. REFERENCES

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Suggested Citation:"9. REFERENCES." National Research Council. 1993. Issues in Risk Assessment. Washington, DC: The National Academies Press. doi: 10.17226/2078.
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ments on this article. An earlier version of this paper was presented on September 6, 1990 in Washington, D.C. at the Workshop on Maximum Tolerated Dose: Implications for Risk Assessment sponsored by the U.S. National Academy of Sciences Committee on Risk Assessment Methodology, and discussed by Drs. Edmund Crouch and Lauren Zeise. A draft of this paper was also presented at the International Environmetrics Conference held in Como, Italy, from September 27-October 2, 1990.

9. References

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Suggested Citation:"9. REFERENCES." National Research Council. 1993. Issues in Risk Assessment. Washington, DC: The National Academies Press. doi: 10.17226/2078.
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Suggested Citation:"9. REFERENCES." National Research Council. 1993. Issues in Risk Assessment. Washington, DC: The National Academies Press. doi: 10.17226/2078.
×

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Suggested Citation:"9. REFERENCES." National Research Council. 1993. Issues in Risk Assessment. Washington, DC: The National Academies Press. doi: 10.17226/2078.
×

Freedman, D.A., Gold, L.S. & Slone, T.H. (1992). How tautological are interspecies correlations of carcinogenic potencies? Technical Report No. 334, Department of Statistics, University of California, Berkeley.


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Suggested Citation:"9. REFERENCES." National Research Council. 1993. Issues in Risk Assessment. Washington, DC: The National Academies Press. doi: 10.17226/2078.
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1.  

Health Protection Branch, Health & Welfare Canada, Ottawa, Ontario, Canada

2.  

Department of Mathematics & Statistics, Carleton University, Ottawa, Canada

3.  

National Center for Toxicological Research, Food & Drug Administration, Jefferson, Arkansas

4.  

Center for Mathematical Sciences, University of Wisconsin-Madison, Madison, Wisconsin

5.  

Department of Mathematical Sciences, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin

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The scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume.

The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures.

The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis.

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